Tetrazine-Ph-NHS ester

Product Name : Tetrazine-Ph-NHS esterDescription:Tetrazine-Ph-NHS ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs.CAS: 1616668-55-3Molecular Weight:313.27Formula: C14H11N5O4Chemical Name: 2,5-dioxopyrrolidin-1-yl 2-acetateSmiles : O=C(CC1C=CC(=CC=1)C1N=NC=NN=1)ON1C(=O)CCC1=OInChiKey: ORWDYVDDJMYIQA-UHFFFAOYSA-NInChi :…

Tos-PEG2-CH2COOH

Product Name : Tos-PEG2-CH2COOHDescription:Tos-PEG2-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.CAS: 1807537-35-4Molecular Weight:318.34Formula: C13H18O7SChemical Name: 2-(2-{2-ethoxy}ethoxy)acetic acidSmiles : CC1=CC=C(C=C1)S(=O)(=O)OCCOCCOCC(O)=OInChiKey: QQHWSZBWDYTXGD-UHFFFAOYSA-NInChi : InChI=1S/C13H18O7S/c1-11-2-4-12(5-3-11)21(16,17)20-9-8-18-6-7-19-10-13(14)15/h2-5H,6-10H2,1H3,(H,14,15)Purity: ≥98%…

Azido-PEG8-NHBoc

Product Name : Azido-PEG8-NHBocDescription:Azido-PEG8-NHBoc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.CAS: 2231845-12-6Molecular Weight:538.63Formula: C23H46N4O10Chemical Name: tert-butyl N-(26-azido-3,6,9,12,15,18,21,24-octaoxahexacosan-1-yl)carbamateSmiles : CC(C)(C)OC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCN==InChiKey: BDFYYRYBZUPGSL-UHFFFAOYSA-NInChi : InChI=1S/C23H46N4O10/c1-23(2,3)37-22(28)25-4-6-29-8-10-31-12-14-33-16-18-35-20-21-36-19-17-34-15-13-32-11-9-30-7-5-26-27-24/h4-21H2,1-3H3,(H,25,28)Purity: ≥98% (or…

Tectorigenin 7-O-Xylosyl Glucoside

Product Name : Tectorigenin 7-O-Xylosyl GlucosideDescription:Tectorigenin 7-O-Xylosyl Glucoside is a glycosidic isoflavone isolated from Pueraria thomsonii flower.CAS: 231288-19-0Molecular Weight:594.52Formula: C27H30O15Chemical Name: 5-hydroxy-3-(4-hydroxyphenyl)-6-methoxy-7-{oxy}methyl)oxan-2-yl]oxy}-4H-chromen-4-oneSmiles : COC1=C(C=C2OC=C(C(=O)C2=C1O)C1C=CC(O)=CC=1)O1O(CO2OC(O)(O)2O)(O)(O)1OInChiKey: MCYJIRFKDCXYCX-YUPZTAPUSA-NInChi : InChI=1S/C27H30O15/c1-37-25-15(6-14-17(21(25)33)18(30)12(7-38-14)10-2-4-11(28)5-3-10)41-27-24(36)22(34)20(32)16(42-27)9-40-26-23(35)19(31)13(29)8-39-26/h2-7,13,16,19-20,22-24,26-29,31-36H,8-9H2,1H3/t13-,16-,19+,20-,22+,23-,24-,26+,27-/m1/s1Purity: ≥98% (or refer…

Iriflophenone

Product Name : IriflophenoneDescription:Iriflophenone, isolated from Aquilaria sinensis, stimulates MCF-7 and T-47D human breast cancer cells proliferation.CAS: 52591-10-3Molecular Weight:246.22Formula: C13H10O5Chemical Name: 2-(4-hydroxybenzoyl)benzene-1,3,5-triolSmiles : OC1C=C(O)C=C(O)C=1C(=O)C1C=CC(O)=CC=1InChiKey: AOJWDTJDEGSHOA-UHFFFAOYSA-NInChi : InChI=1S/C13H10O5/c14-8-3-1-7(2-4-8)13(18)12-10(16)5-9(15)6-11(12)17/h1-6,14-17HPurity: ≥98% (or refer…

Astressin

Product Name : AstressinDescription:Astressin is a potent corticotropin releasing factor (CRF) antagonist.CAS: 170809-51-5Molecular Weight:3563.16Formula: C161H269N49O42Chemical Name: (4S)-4-{carbamoyl}-2-methylbutyl]carbamoyl}-3-carboxypropyl]carbamoyl}pentyl]carbamoyl}-3-methylbutyl]carbamoyl}pentyl]carbamoyl}-4-carbamimidamidobutyl]carbamoyl}-2-carbamoylethyl]carbamoyl}-3--6-methyl-2,5,8,12-tetraoxo-1,4,7,13-tetraazacyclooctadecan-9-yl]carbamoyl}-3-carbamoylpropyl]carbamoyl}ethyl]carbamoyl}-3-methylbutyl]carbamoyl}-3-carbamoylpropyl]carbamoyl}-3-carboxypropyl]carbamoyl}ethyl]carbamoyl}-4-carbamimidamidobutyl]carbamoyl}ethyl]carbamoyl}pentyl]carbamoyl}-3-carboxypropyl]carbamoyl}-3-methylbutyl]carbamoyl}-2-methylpropyl]carbamoyl}-4--3-(1H-imidazol-4-yl)propanamido]-4-methylpentanamido]-4-methylpentanamido]-5-carbamimidamidopentanamido]butanoic acidSmiles : C(CC)(NC(=O)(NC(=O)(CCC(O)=O)NC(=O)(CCCC)NC(=O)(CC(C)C)NC(=O)(CCCCN)NC(=O)(CCCNC(N)=N)NC(=O)(CC(N)=O)NC(=O)1CCCCNC(=O)CC(NC(=O)(CCC(N)=O)NC(=O)(C)NC(=O)(CC(C)C)NC(=O)(CCC(N)=O)NC(=O)(CCC(O)=O)NC(=O)(C)NC(=O)(CCCNC(N)=N)NC(=O)(C)NC(=O)(CCCC)NC(=O)(CCC(O)=O)NC(=O)(CC(C)C)NC(=O)(NC(=O)(CCC(O)=O)NC(=O)(CCCNC(N)=N)NC(=O)(CC(C)C)NC(=O)(CC(C)C)NC(=O)(CC2=CNC=N2)NC(=O)(N)CC2C=CC=CC=2)C(C)C)C(=O)N(C)C(=O)N(CC2=CNC=N2)C(=O)N1)(C)CC)C(N)=OInChiKey: HPYIIXJJVYSMCV-MGDXKYBTSA-NInChi : InChI=1S/C161H269N49O42/c1-23-27-41-96(189-145(239)107(52-59-123(217)218)199-152(246)114(71-84(13)14)207-157(251)126(85(15)16)208-147(241)108(53-60-124(219)220)197-140(234)102(47-38-66-179-161(172)173)193-151(245)112(69-82(9)10)204-153(247)113(70-83(11)12)205-155(249)116(74-94-77-175-79-181-94)201-134(228)95(163)72-92-39-30-29-31-40-92)135(229)182-88(19)130(224)186-100(45-36-64-177-159(168)169)136(230)183-89(20)131(225)188-106(51-58-122(215)216)144(238)195-104(49-56-119(165)212)146(240)202-110(67-80(5)6)149(243)185-90(21)132(226)187-103(48-55-118(164)211)143(237)196-105-50-57-121(214)176-63-35-33-44-99(192-154(248)115(73-93-76-174-78-180-93)200-133(227)91(22)184-137(105)231)142(236)206-117(75-120(166)213)156(250)194-101(46-37-65-178-160(170)171)139(233)190-98(43-32-34-62-162)141(235)203-111(68-81(7)8)150(244)191-97(42-28-24-2)138(232)198-109(54-61-125(221)222)148(242)210-128(87(18)26-4)158(252)209-127(129(167)223)86(17)25-3/h29-31,39-40,76-91,95-117,126-128H,23-28,32-38,41-75,162-163H2,1-22H3,(H2,164,211)(H2,165,212)(H2,166,213)(H2,167,223)(H,174,180)(H,175,181)(H,176,214)(H,182,229)(H,183,230)(H,184,231)(H,185,243)(H,186,224)(H,187,226)(H,188,225)(H,189,239)(H,190,233)(H,191,244)(H,192,248)(H,193,245)(H,194,250)(H,195,238)(H,196,237)(H,197,234)(H,198,232)(H,199,246)(H,200,227)(H,201,228)(H,202,240)(H,203,235)(H,204,247)(H,205,249)(H,206,236)(H,207,251)(H,208,241)(H,209,252)(H,210,242)(H,215,216)(H,217,218)(H,219,220)(H,221,222)(H4,168,169,177)(H4,170,171,178)(H4,172,173,179)/t86-,87-,88-,89-,90-,91-,95+,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,126-,127-,128-/m0/s1Purity: ≥98% (or refer to the Certificate of…

Cbz-NH-PEG3-CH2COOH

Product Name : Cbz-NH-PEG3-CH2COOHDescription:Cbz-NH-PEG3-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.CAS: 462100-05-6Molecular Weight:341.36Formula: C16H23NO7Chemical Name: 2-{2-amino}ethoxy)ethoxy]ethoxy}acetic acidSmiles : OC(=O)COCCOCCOCCNC(=O)OCC1C=CC=CC=1InChiKey: DMBZCDPECWJRJR-UHFFFAOYSA-NInChi : InChI=1S/C16H23NO7/c18-15(19)13-23-11-10-22-9-8-21-7-6-17-16(20)24-12-14-4-2-1-3-5-14/h1-5H,6-13H2,(H,17,20)(H,18,19)Purity: ≥98%…

(±)-Lisofylline-d6

Product Name : (±)-Lisofylline-d6Description:Product informationCAS: 1185995-26-9Molecular Weight:286.36Formula: C13H20N4O3Chemical Name: 1-(5-hydroxyhexyl)-3,7-di(²H₃)methyl-2,3,6,7-tetrahydro-1H-purine-2,6-dioneSmiles : C()()N1C=NC2=C1C(=O)N(CCCCC(C)O)C(=O)N2C()()InChiKey: NSMXQKNUPPXBRG-XERRXZQWSA-NInChi : InChI=1S/C13H20N4O3/c1-9(18)6-4-5-7-17-12(19)10-11(14-8-15(10)2)16(3)13(17)20/h8-9,18H,4-7H2,1-3H3/i2D3,3D3Purity: ≥98% (or refer to the Certificate of Analysis)Shipping Condition: Shipped under ambient temperature as non-hazardous…

WAY 208466 dihydrochloride

Product Name : WAY 208466 dihydrochlorideDescription:Product informationCAS: 1207064-61-6Molecular Weight:420.33Formula: C17H20Cl2FN3O2SChemical Name: {2-pyridin-1-yl]ethyl}dimethylamine dihydrochlorideSmiles : Cl.Cl.CN(C)CCN1C=C(C2C=CC=NC1=2)S(=O)(=O)C1C=C(F)C=CC=1InChiKey: BAOHMLBVCLITHA-UHFFFAOYSA-NInChi : InChI=1S/C17H18FN3O2S.2ClH/c1-20(2)9-10-21-12-16(15-7-4-8-19-17(15)21)24(22,23)14-6-3-5-13(18)11-14;;/h3-8,11-12H,9-10H2,1-2H3;2*1HPurity: ≥98% (or refer to the Certificate of Analysis)Shipping Condition: Shipped under ambient…

NGD 94-1

Product Name : NGD 94-1Description:Product informationCAS: 178928-68-2Molecular Weight:320.39Formula: C18H20N6Chemical Name: 2-{4-piperazin-1-yl}pyrimidineSmiles : C(C1=CN=C(N1)C1C=CC=CC=1)N1CCN(CC1)C1N=CC=CN=1InChiKey: OTVQCHUIPJYASM-UHFFFAOYSA-NInChi : InChI=1S/C18H20N6/c1-2-5-15(6-3-1)17-21-13-16(22-17)14-23-9-11-24(12-10-23)18-19-7-4-8-20-18/h1-8,13H,9-12,14H2,(H,21,22)Purity: ≥98% (or refer to the Certificate of Analysis)Shipping Condition: Shipped under ambient temperature as…

Cystamine dihydrochloride

Product Name : Cystamine dihydrochlorideDescription:Product informationCAS: 56-17-7Molecular Weight:225.20Formula: C4H14Cl2N2S2Chemical Name: 2-ethan-1-amine dihydrochlorideSmiles : Cl.Cl.NCCSSCCNInChiKey: YUFRRMZSSPQMOS-UHFFFAOYSA-NInChi : InChI=1S/C4H12N2S2.2ClH/c5-1-3-7-8-4-2-6;;/h1-6H2;2*1HPurity: ≥98% (or refer to the Certificate of Analysis)Shipping Condition: Shipped under ambient temperature…

4-Fluoro-7-nitrobenzofurazan

Product Name : 4-Fluoro-7-nitrobenzofurazanSynonym: IUPAC Name : 4-fluoro-7-nitro-2,1,3-benzoxadiazoleCAS NO.:29270-56-2Molecular Weight : Molecular formula: C6H2FN3O3Smiles: (=O)C1=CC=C(F)C2=NON=C12Description: 4-Chloro-7-nitrobenzofurazan (NBD-chloride) was used in the following studies, Synthesis of fluorescent phospholipid-derivative, NBD-didecanoylphosphatidylethanolamine, Synthesis of…

Enrofloxacin

Product Name : EnrofloxacinSynonym: IUPAC Name : 1-cyclopropyl-7-(4-ethylpiperazin-1-yl)-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acidCAS NO.:93106-60-6Molecular Weight : Molecular formula: C19H22FN3O3Smiles: CCN1CCN(CC1)C1=C(F)C=C2C(=O)C(=CN(C3CC3)C2=C1)C(O)=ODescription: Enrofloxacin is a broad spectrum antibiotic bactericidal agent used in veterinary medicine to treat…

(7-Azabenzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate, 98%

Product Name : (7-Azabenzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate, 98%Synonym: IUPAC Name : hexafluoro-λ⁵-phosphanuide; tris(pyrrolidin-1-yl)({3H-triazolopyridin-3-yloxy})phosphaniumCAS NO.Umeclidinium bromide :156311-83-0Molecular Weight : Molecular formula: C17H27F6N7OP2Smiles: F(F)(F)(F)(F)F.Omaveloxolone C1CCN(C1)(ON1N=NC2=CC=CN=C12)(N1CCCC1)N1CCCC1Description: PMID:23551549 MedChemExpress (MCE) offers a wide range of high-quality…

Aloin

Product Name : AloinSynonym: IUPAC Name : (10R)-1,8-dihydroxy-3-(hydroxymethyl)-10--9,10-dihydroanthracen-9-oneCAS NO.:1415-73-2Molecular Weight : Molecular formula: C21H22O9Smiles: OC1O((O)(O)1O)1C2=CC=CC(O)=C2C(=O)C2=C(O)C=C(CO)C=C12Description: Aloe exudant, used as a stimulant-laxativeSelinexor Netupitant PMID:23626759 MedChemExpress (MCE) offers a wide range of…

N,O-Bis(trimethylsilyl)trifluoroacetamide, with 1% TMCS, packaged under Argon in resealable ChemSeal™ bottles

Product Name : N,O-Bis(trimethylsilyl)trifluoroacetamide, with 1% TMCS, packaged under Argon in resealable ChemSeal™ bottlesSynonym: IUPAC Name : trimethylsilyl 2,2,2-trifluoro-N-(trimethylsilyl)ethanimidateCAS NO.:25561-30-2Molecular Weight : Molecular formula: C8H18F3NOSi2Smiles: C(C)(C)OC(=N(C)(C)C)C(F)(F)FDescription: N,O-Bis(trimethylsilyl)trifluoroacetamide is used for…

Hemin (porcine), 97+%

Product Name : Hemin (porcine), 97+%Synonym: IUPAC Name : iron(3+) 4,20-bis(2-carboxyethyl)-9,14-diethenyl-5,10,15,19-tetramethyl-21,22,23,24-tetraazapentacyclotetracosa-1(20),2,4,6(24),7,9,11,13(22),14,16,18-undecaene-21,23-diideCAS NO.:16009-13-5Molecular Weight : Molecular formula: C34H32FeN4O4Smiles: .Sacituzumab govitecan CC1=C2C(C=C3N=C(C=C4C(=CC5=NC(=C2)C(C)=C5C=C)C(C)=C4C=C)C(C)=C3CCC(O)=O)=C1CCC(O)=ODescription: Hemin is used in cellular protection and control mechanism.Tegafur-Uracil It…

1-Docosanol, 98%

Product Name : 1-Docosanol, 98%Synonym: IUPAC Name : docosan-1-olCAS NO.:661-19-8Molecular Weight : Molecular formula: C22H46OSmiles: CCCCCCCCCCCCCCCCCCCCCCODescription: Crizotinib Bathophenanthroline PMID:23907051 MedChemExpress (MCE) offers a wide range of high-quality research chemicals and…

Phenanthrene, 97%

Product Name : Phenanthrene, 97%Synonym: IUPAC Name : phenanthreneCAS NO.Donepezil Hydrochloride :85-01-8Molecular Weight : Molecular formula: C14H10Smiles: C1=CC=C2C(C=CC3=CC=CC=C23)=C1Description: Lanosterol PMID:23563799 MedChemExpress (MCE) offers a wide range of high-quality research chemicals…

Flavone, 99+%

Product Name : Flavone, 99+%Synonym: IUPAC Name : 2-phenyl-4H-chromen-4-oneCAS NO.Omaveloxolone :525-82-6Molecular Weight : Molecular formula: C15H10O2Smiles: O=C1C=C(OC2=CC=CC=C12)C1=CC=CC=C1Description: Colistin sulfate PMID:25269910 MedChemExpress (MCE) offers a wide range of high-quality research chemicals…

2-Phenoxypropylamine, 98%

Product Name : 2-Phenoxypropylamine, 98%Synonym: IUPAC Name : 2-phenoxypropan-1-amine hydrochlorideCAS NO.:6437-49-6Molecular Weight : Molecular formula: C9H14ClNOSmiles: Cl.Fexofenadine hydrochloride CC(CN)OC1=CC=CC=C1Description: 2-Phenoxypropylamine is used as pharmaceutical intermediate.Epoprostenol sodium PMID:30125989

4-Methylcatechol, 96%

Product Name : 4-Methylcatechol, 96%Synonym: IUPAC Name : 4-methylbenzene-1,2-diolCAS NO.Asiatic acid :452-86-8Molecular Weight : Molecular formula: C7H8O2Smiles: CC1=CC=C(O)C(O)=C1Description: 4-Methylcatechol is used to synthesize antimicrobial, antioxidant.Omaveloxolone It also acts as effective…

6-Maleimidohexanoic acid

Product Name : 6-Maleimidohexanoic acidSynonym: IUPAC Name : 6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanoic acidCAS NO.:55750-53-3Molecular Weight : Molecular formula: C10H13NO4Smiles: OC(=O)CCCCCN1C(=O)C=CC1=ODescription: 6-Maleimidohexanoic acid is used as a probe for introducing maleimides groups into biomolecules…

3-(2-Pyridyl)-5,6-diphenyl-1,2,4-triazine-p,p’-disulfonic acid, disodium salt hydrat

Product Name : 3-(2-Pyridyl)-5,6-diphenyl-1,2,4-triazine-p,p'-disulfonic acid, disodium salt hydratSynonym: IUPAC Name : disodium 4-benzene-1-sulfonateCAS NO.:1264198-47-1Molecular Weight : Molecular formula: C20H12N4Na2O6S2Smiles: .Galcuronokinase .GDNF Protein, Human S(=O)(=O)C1=CC=C(C=C1)C1=C(N=C(N=N1)C1=CC=CC=N1)C1=CC=C(C=C1)S()(=O)=ODescription: PMID:23833812

Ursolic acid, 95%

Product Name : Ursolic acid, 95%Synonym: IUPAC Name : (1S,2R,4aS,6aS,6bR,8aR,10S,12aR,12bR,14bS)-10-hydroxy-1,2,6a,6b,9,9,12a-heptamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-4a-carboxylic acidCAS NO.:77-52-1Molecular Weight : Molecular formula: C30H48O3Smiles: C1CC2(CC3(C)C(=CC45(C)CC(O)C(C)(C)5CC34C)21C)C(O)=ODescription: Trimethobenzamide hydrochloride Clopidogrel PMID:23543429

Owfrequencyoffamilialpituitarytumors, thesmallsizeofaffectedfamilies,andtheverylowprevalenceof mutationswithinthesefamilies,costlygeneticscreeningisnotyet convincinglywarranted.Accuraterelativelylow-costmeasurement ofserumIGF1levelsiscurrentlythemosteffectivescreeningfor affectedpatientswithGH-secretingpituitarytumors. Acromegaly

Owfrequencyoffamilialpituitarytumors, thesmallsizeofaffectedfamilies,andtheverylowprevalenceof mutationswithinthesefamilies,costlygeneticscreeningisnotyet convincinglywarranted.Accuraterelativelylow-costmeasurement ofserumIGF1levelsiscurrentlythemosteffectivescreeningfor affectedpatientswithGH-secretingpituitarytumors. Acromegaly remedy Severaltreatmentoptionsarecurrentlyavailableforacromegaly (Table2). Surgery ResectionofGH-secretingpituitaryadenomasistechnicallychallengingbecauseoftheanatomicinaccessibilityofthepituitary andbonysellarconfinesandtheproximityofvitalbrainandvascularstructures.Functioningtumormicrofociofteninvadedural spaces,arenotreadilyvisibleatsurgery,andcontinuetosecrete GHaftertumorresection.GH-secretingtumorshaveapropensitytoinvadelaterallyintothecavernoussinus,precludingsafe resection.Tumor-associatedinternalcarotidarterytortuosityand microaneurysmsalsorequiresurgicalcautionandalertness.Over 90 ofresectionsareperformedviaanendonasaltranssphenoidal strategy,oftenwithminimallyinvasiveendoscopictechniques. ComputerizedimageguidanceandintraoperativeMRIcoupled with improvement of microinstrumentation and optics have resultedinsafe,helpful,andminimallytraumaticprocedures whenperformedbyskilledandexperiencedneurosurgeons(S23).…

Hyl succinimidyl carbonate 1-O-Benzotriazole-N,N,N’,N’-tetramethyl-uromium-hexafluoro-phosphate Hydrochloric acid Histidine

Hyl succinimidyl carbonate 1-O-Benzotriazole-N,N,N',N'-tetramethyl-uromium-hexafluoro-phosphate Hydrochloric acid Histidine 1-Hydroxybenzotriazole High-performance liquid chromatography Higher resolution mass spectra Leucine Lithium hydroxide Methanol Magnesium sulfate Methyltrityl Mass-to-charge ratio Sodium bicarbonateNIH-PA Author Manuscript NIH-PA Author…

P_IGA_357344 Sc3_SNP_IGA_358948 0.0 2.9 4.three five.7 10.2 13.0 14.0 17.5 19.0 22.0 25.1 28.2 29.7 30.3 31.0 34.0 38.7 40.three 41.9 43.four 49.eight 52.9 57.four 57.8 58.4 59.2 60.six 67.0 70.LG3,4-Dimethylstyrene_EJ/AA1,3,8-p-Menthatriene_EJ

P_IGA_357344 Sc3_SNP_IGA_358948 0.0 two.9 4.three five.7 10.2 13.0 14.0 17.five 19.0 22.0 25.1 28.two 29.7 30.three 31.0 34.0 38.7 40.3 41.9 43.four 49.8 52.9 57.four 57.eight 58.4 59.two 60.six 67.0…