Product Name :
TAMRA-PEG4-acid
Description:
TAMRA-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
CAS:
1909223-02-4
Molecular Weight:
677.74
Formula:
C36H43N3O10
Chemical Name:
5-[(14-carboxy-3,6,9,12-tetraoxatetradecan-1-yl)carbamoyl]-2-[6-(dimethylamino)-3-(dimethyliminiumyl)-3H-xanthen-9-yl]benzoate
Smiles :
CN(C)C1=CC2OC3=CC(C=CC3=C(C3=CC=C(C=C3C([O-])=O)C(=O)NCCOCCOCCOCCOCCC(O)=O)C=2C=C1)=[N+](C)C
InChiKey:
AZESQZROUFRXLP-UHFFFAOYSA-N
InChi :
InChI=1S/C36H43N3O10/c1-38(2)25-6-9-28-31(22-25)49-32-23-26(39(3)4)7-10-29(32)34(28)27-8-5-24(21-30(27)36(43)44)35(42)37-12-14-46-16-18-48-20-19-47-17-15-45-13-11-33(40)41/h5-10,21-23H,11-20H2,1-4H3,(H2-,37,40,41,42,43,44)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Alvespimycin} site|{Alvespimycin} Metabolic Enzyme/Protease|{Alvespimycin} Immunology/Inflammation|{Alvespimycin} Purity & Documentation|{Alvespimycin} Formula|{Alvespimycin} manufacturer}
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.{{Buloxibutid} medchemexpress|{Buloxibutid} Angiotensin Receptor|{Buloxibutid} TGF-beta/Smad|{Buloxibutid} Biological Activity|{Buloxibutid} In Vitro|{Buloxibutid} manufacturer}
Additional information:
TAMRA-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.|Product information|CAS Number: 1909223-02-4|Molecular Weight: 677.74|Formula: C36H43N3O10|Chemical Name: 5-[(14-carboxy-3,6,9,12-tetraoxatetradecan-1-yl)carbamoyl]-2-[6-(dimethylamino)-3-(dimethyliminiumyl)-3H-xanthen-9-yl]benzoate|Smiles: CN(C)C1=CC2OC3=CC(C=CC3=C(C3=CC=C(C=C3C([O-])=O)C(=O)NCCOCCOCCOCCOCCC(O)=O)C=2C=C1)=[N+](C)C|InChiKey: AZESQZROUFRXLP-UHFFFAOYSA-N|InChi: InChI=1S/C36H43N3O10/c1-38(2)25-6-9-28-31(22-25)49-32-23-26(39(3)4)7-10-29(32)34(28)27-8-5-24(21-30(27)36(43)44)35(42)37-12-14-46-16-18-48-20-19-47-17-15-45-13-11-33(40)41/h5-10,21-23H,11-20H2,1-4H3,(H2-,37,40,41,42,43,44)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.PMID:33188646 |Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.|Products are for research use only. Not for human use.|