Product Name :
Imidapril hydrochloride
Description:
Imidapril hydrochloride (TA-6366) is the hydrochloride salt of Imidapril, an angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity.
CAS:
89396-94-1
Molecular Weight:
441.91
Formula:
C20H28ClN3O6
Chemical Name:
3-2-[(1-ethoxy-1-oxo-4-phenylbutan-2-yl)amino]propanoyl-1-methyl-2-oxoimidazolidine-4-carboxylic acid hydrochloride
Smiles :
Cl.CN1CC(C(O)=O)N(C1=O)C(=O)C(C)NC(CCC1C=CC=CC=1)C(=O)OCC
InChiKey:
LSLQGMMMRMDXHN-UHFFFAOYSA-N
InChi :
InChI=1S/C20H27N3O6.ClH/c1-4-29-19(27)15(11-10-14-8-6-5-7-9-14)21-13(2)17(24)23-16(18(25)26)12-22(3)20(23)28;/h5-9,13,15-16,21H,4,10-12H2,1-3H3,(H,25,26);1H
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.1,1-Dimethyl-4-acetylpiperazinium supplier
Shelf Life:
≥12 months if stored properly.Quizartinib Formula
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Imidapril hydrochloride (TA-6366) is the hydrochloride salt of Imidapril, an angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity.PMID:33939949 |Product information|CAS Number: 89396-94-1|Molecular Weight: 441.91|Formula: C20H28ClN3O6|Chemical Name: 3-2-[(1-ethoxy-1-oxo-4-phenylbutan-2-yl)amino]propanoyl-1-methyl-2-oxoimidazolidine-4-carboxylic acid hydrochloride|Smiles: Cl.CN1CC(C(O)=O)N(C1=O)C(=O)C(C)NC(CCC1C=CC=CC=1)C(=O)OCC|InChiKey: LSLQGMMMRMDXHN-UHFFFAOYSA-N|InChi: InChI=1S/C20H27N3O6.ClH/c1-4-29-19(27)15(11-10-14-8-6-5-7-9-14)21-13(2)17(24)23-16(18(25)26)12-22(3)20(23)28;/h5-9,13,15-16,21H,4,10-12H2,1-3H3,(H,25,26);1H|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 50 mg/mL (113.15 mM; Need ultrasonic). H2O : 50 mg/mL (113.15 mM; Need ultrasonic).|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|As a prodrug, Imidapril is converted by hydrolysis in the liver into its active form imidaprilat. Imidaprilat competitively binds to and inhibits ACE, thereby blocking the conversion of angiotensin I to angiotensin II. This prevents the potent vasoconstrictive actions of angiotensin II and results in vasodilation. Imidaprilat also decreases angiotensin II-induced aldosterone secretion by the adrenal cortex, which leads to an increase in sodium excretion and subsequently increases water outflow.|Products are for research use only. Not for human use.|