Product Name :
FAPI-34
Description:
FAPI-34 is a fibroblast-activating protein (FAP) inhibitor with favorable pharmacokinetic and biochemical properties. (patent WO2019154886A1).
CAS:
2374782-07-5
Molecular Weight:
1166.06
Formula:
C50H57F2N13O18
Chemical Name:
(3S, 3’S)-3, 3′-((2, 2′-((((2-(4-(3-((4-((2-((S)-2-cyano-4, 4-difluoropyrrolidin-1-yl)-2-oxoethyl)carbamoyl)quinolin-6-yl)oxy)propyl)piperazin-1-yl)-2-oxoethyl)azanediyl)bis(methylene))bis(1H-imidazole-2, 1-diyl))bis(acetyl))bis(azanediyl))bis(propane-1, 1, 3-tricarboxylic acid)
Smiles :
N#C[C@@H]1CC(F)(F)CN1C(=O)CNC(=O)C1=CC=NC2=CC=C(C=C21)OCCCN1CCN(CC1)C(=O)CN(CC1=NC=CN1CC(=O)N[C@@H](CC(C(O)=O)C(O)=O)C(O)=O)CC1=NC=CN1CC(=O)N[C@@H](CC(C(O)=O)C(O)=O)C(O)=O
InChiKey:
FPOZMWSPTRNDPQ-UVXHQIPUSA-N
InChi :
InChI=1S/C50H57F2N13O18/c51-50(52)19-28(20-53)65(27-50)41(68)21-57-43(70)30-4-5-54-34-3-2-29(16-31(30)34)83-15-1-8-60-11-13-62(14-12-60)42(69)26-61(22-37-55-6-9-63(37)24-39(66)58-35(48(79)80)17-32(44(71)72)45(73)74)23-38-56-7-10-64(38)25-40(67)59-36(49(81)82)18-33(46(75)76)47(77)78/h2-7,9-10,16,28,32-33,35-36H,1,8,11-15,17-19,21-27H2,(H,57,70)(H,58,66)(H,59,67)(H,71,72)(H,73,74)(H,75,76)(H,77,78)(H,79,80)(H,81,82)/t28-,35-,36-/m0/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
FAPI-34 is a fibroblast-activating protein (FAP) inhibitor with favorable pharmacokinetic and biochemical properties. (patent WO2019154886A1).|Product information|CAS Number: 2374782-07-5|Molecular Weight: 1166.06|Formula: C50H57F2N13O18|Chemical Name: (3S, 3’S)-3, 3′-((2, 2′-((((2-(4-(3-((4-((2-((S)-2-cyano-4, 4-difluoropyrrolidin-1-yl)-2-oxoethyl)carbamoyl)quinolin-6-yl)oxy)propyl)piperazin-1-yl)-2-oxoethyl)azanediyl)bis(methylene))bis(1H-imidazole-2, 1-diyl))bis(acetyl))bis(azanediyl))bis(propane-1, 1, 3-tricarboxylic acid)|Smiles: N#C[C@@H]1CC(F)(F)CN1C(=O)CNC(=O)C1=CC=NC2=CC=C(C=C21)OCCCN1CCN(CC1)C(=O)CN(CC1=NC=CN1CC(=O)N[C@@H](CC(C(O)=O)C(O)=O)C(O)=O)CC1=NC=CN1CC(=O)N[C@@H](CC(C(O)=O)C(O)=O)C(O)=O|InChiKey: FPOZMWSPTRNDPQ-UVXHQIPUSA-N|InChi: InChI=1S/C50H57F2N13O18/c51-50(52)19-28(20-53)65(27-50)41(68)21-57-43(70)30-4-5-54-34-3-2-29(16-31(30)34)83-15-1-8-60-11-13-62(14-12-60)42(69)26-61(22-37-55-6-9-63(37)24-39(66)58-35(48(79)80)17-32(44(71)72)45(73)74)23-38-56-7-10-64(38)25-40(67)59-36(49(81)82)18-33(46(75)76)47(77)78/h2-7,9-10,16,28,32-33,35-36H,1,8,11-15,17-19,21-27H2,(H,57,70)(H,58,66)(H,59,67)(H,71,72)(H,73,74)(H,75,76)(H,77,78)(H,79,80)(H,81,82)/t28-,35-,36-/m0/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.GL0388 In stock |Shelf Life: ≥12 months if stored properly.Miriplatin medchemexpress |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:32484513 |Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|