TWEAK R/TNFRSF12 Antibody (ITEM-1) Summary
Human Fn14 transfected P815
IgG1 Kappa
Monoclonal
Mouse
Protein A or G purified
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Applications/Dilutions
- Flow Cytometry
This antibody is reported to work in WB and IHC per literature. For immunofluorescent staining, the suggested use of this reagent is less than 0.5 ug per million cells in 100 ul volume or 100 ul of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Reactivity Notes
Human.
Packaging, Storage & Formulations
Store at 4C. Do not freeze.
PBS (pH 7.2)
No Preservative
1 mg/ml
Protein A or G purified
Alternate Names for TWEAK R/TNFRSF12 Antibody (ITEM-1)
- CD266 antigen
- CD266
- FGF-inducible 14
- Fibroblast growth factor-inducible immediate-early response protein 14
- Fn14
- FN14tumor necrosis factor receptor superfamily member 12A
- TNFRSF12
- TNFRSF12A
- tumor necrosis factor receptor superfamily, member 12A
- TWEAK R
- TWEAKR
- tweak-receptor
- type I transmembrane protein Fn14
Background
TWEAK receptor is also known as fibroblast growth factor inducible 14 kD protein (Fn14) or CD266. It is a 14 kD transmembrane protein that is expressed on a variety of tissue types. This receptor binds TWEAK and interacts with the cytoplasmic proteins TRAF1, 2, and 3. The TWEAK receptor is rapidly induced during liver regeneration and m play a role in hepatocyte growth. TWEAK receptor engagement can induce cell death and may play a role in inflammation.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.