jbc.M112.382952

IL-9 R Antibody (RM0115-12F43) Summary

    Immunogen
    Mouse recombinant protein of the extracellular domain of IL-9 R
    Specificity
    This was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat immunized with mouse recombinant protein of the extracellular domain of IL-9 R.
    Isotype
    IgG2
    Clonality
    Monoclonal
    Host
    Rat
    Gene
    IL9R
    Purity
    Protein G purified
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Applications/Dilutions

    Dilutions
        Western Blot 1:500-1:1000
    Application Notes
    This antibody detects mouse IL-9 R in Western blotting.

Reactivity Notes

Mouse.

Packaging, Storage & Formulations

    Storage
    Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
    Buffer
    A 0.2 um filtered solution in PBS
    Preservative
    No Preservative
    Concentration
    LYOPH
    Purity
    Protein G purified
    Reconstitution Instructions
    Reconstitute with 0.2 ml sterilized PBS to a final concentration of 0.5 mg/ml.

Alternate Names for IL-9 R Antibody (RM0115-12F43)

      CD129 antigen
      CD129
      IL-9 R
      IL-9 receptor
      IL9R
      IL-9R
      interleukin 9 receptor
      interleukin-9 receptor

Background

Human Interleukin 9 (IL9) was first identified based on its proliferative activity on a human myeloid leukemic cell line. Human IL9 stimulates the proliferation of the human megakaryocytic leukemic cell line M07e. Human IL9 supports erythroid colony formation and synergizes with IL4 in the production of IgE and IgG. The interleukin 9 receptor is a member of the hematopoietin receptor superfamily. The cDNAs encoding mouse and human IL9 receptors have been isolated. The deduced mouse and human transmembrane proteins, sharing 53% amino acid sequence identity, contain 468 and 533 amino acid residues, respectively. A number of isoforms of IL9R, including a putative soluble form, have also been identified. The IL9 receptor is expressed in a variety of hematopoietic cells including T cells, neutrophils, mast cells, and macrophages.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

LY3023414

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