CEACAM1/CD66a Antibody (2F10) Summary
CEACAM1 (AAH14473 305 a.a. – 414 a.a.) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. VTGCNRTTVKTIIVTELSPVVAKPQIKASKTTVTGDKDSVNLTCSTNDTGISIRWFFKNQSLPSSERMKLSQGNTTLSINPVKREDAGTYWCEVFNPISKNQSDPIMLNV
CEACAM1 – carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
IgG2a Kappa
Monoclonal
Mouse
CEACAM1
IgG purified
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Applications/Dilutions
- ELISA
Antibody reactivity against recombinant protein on ELISA. GST alone used as a negative control.
Packaging, Storage & Formulations
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
PBS (pH 7.4)
No Preservative
IgG purified
Notes
Quality control test: Antibody Reactive Against Recombinant Protein.
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for CEACAM1/CD66a Antibody (2F10)
- antigen CD66
- BGP1
- BGP-1
- BGP1BGPBiliary glycoprotein 1
- BGPI
- Biliary Glycoprotein 1
- biliary glycoprotein adhesion molecule
- carcinoembryonic antigen-related cell adhesion molecule 1 (biliaryglycoprotein)
- carcinoembryonic antigen-related cell adhesion molecule 1
- CD66a antigen
- CD66a
- Cea-1
- CEACAM1
- CEACAM-1
- Hv-1
- Hv-2
- MHVR
Background
This gene encodes a member of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily. Two subgroups of the CEA family, the CEA cell adhesion molecules and the pregnancy-specific glycoproteins, are located within a 1.2 Mb cluster on the long arm of chromosome 19. Eleven pseudogenes of the CEA cell adhesion molecule subgroup are also found in the cluster. The encoded protein was originally described in bile ducts of liver as biliary glycoprotein. Subsequently, it was found to be a cell-cell adhesion molecule detected on leukocytes, epithelia, and endothelia. The encoded protein mediates cell adhesion via homophilic as well as heterophilic binding to other proteins of the subgroup. Multiple cellular activities have been attributed to the encoded protein, including roles in the differentiation and arrangement of tissue three-dimensional structure, angiogenesis, apoptosis, tumor suppression, metastasis, and the modulation of innate and adaptive immune responses. Multiple transcript variants encoding different isoforms have been reported, but the full-length nature of only two has been determined.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.