Phospholipid Scramblase 1/PLSCR1 Antibody (1F9) Summary
PLSCR1 (AAH32718, 1 a.a. – 318 a.a.) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MDKQNSQMNASHPETNLPVGYPPQYPPTAFQGPPGYSGYPGPQVSYPPPPAGHSGPGPAGFPVPNQPVYNQPVYNQPVGAAGVPWMPAPQPPLNCPPGLEYLSQIDQILIHQQIKLLEVLTGFETNNKYEIKNSFGQRVYFAAEDTDCCTRNCCGPSRPFTLRIIDNMGQEVITLERPLRCSSCCCPCCLQEIEIQAPPGVPIGYVIQTWHPCLPKFTIQNEKREDVLKISGPCVVCSCCGDVDFEIKSLDEQCVVGKISKHWTGILREAFTDADNFGIQFPLDLDVKMKAVMIGACFLIDFMFFESTGSQEQKSGVW
Cell Membrane (single-pass type II membrane protein) and Nuclear.
PLSCR1 – phospholipid scramblase 1
IgG2a Kappa
Monoclonal
Mouse
PLSCR1
IgG purified
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Applications/Dilutions
- ELISA
Antibody reactivity against recombinant protein on ELISA.
Packaging, Storage & Formulations
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
PBS (pH 7.4)
No Preservative
IgG purified
Notes
Quality control test: Antibody Reactive Against Recombinant Protein.
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for Phospholipid Scramblase 1/PLSCR1 Antibody (1F9)
- Erythrocyte phospholipid scramblase
- MMTRA1B
- MMTRA1BCa(2+)-dependent phospholipid scramblase 1
- Phospholipid Scramblase 1
- PL scramblase 1
- PLSCR1
Background
Phospholipid scramblase 1 (PLSCR1) is a member of the PLSCR protein family. These proteins are ATP-independent lipid translocators localized to the plasma membrane and is involved in a calcium dependent, nonspecific and rapid redistribution (scrambling) of phospholipids when a perturbation of plasma membrane asymmetry is needed for the cell (e.g. following cell activation, injury, or apoptosis). The expression of PLSCR1 is found in a variety of tissue and can be stress-induced. Upon stimulation (e.g. interferon stimulation), a portion of newly synthesized PLSCR1 is imported into the nucleus (instead of inserted into the plasma membrane) and interacts with DNA, consistent with a role in gene regulation. PLSCR1 may be closely associated with the pathophysiology underlying infection and inflammation, which manifest marked changes in energy consumption and lipid metabolism.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
product targets :　PIKfyve inhibitors