ITFG1 Antibody (936213) [Alexa Fluor® 488] Summary
Human embryonic kidney cell line HEK293-derived human ITFG1
Met1-Ile566
Accession # Q8TB96
Met1-Ile566
Accession # Q8TB96
Detects human ITFG1 in direct ELISAs.
IgG2b
Monoclonal
Mouse
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Applications/Dilutions
- Flow Cytometry 0.25-1 ug/10^6 cells
Packaging, Storage & Formulations
Store the unopened product at 2 – 8 °C. Do not use past expiration date.
Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.
Notes
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for ITFG1 Antibody (936213) [Alexa Fluor® 488]
- CDA08
- integrin alpha FG-GAP repeat containing 1,2310047C21Rik
- Integrin-alpha FG-GAP repeat-containing protein 1
- ITFG1
- Protein TIP
- T-cell immunomodulatory protein
- TIP
- TIPT cell immunomodulatory protein
Background
Integrin-alpha FG-GAP repeat-containing protein 1 (ITFG1), also known as T cell immunomodulatory protein (TIP), was initially identified using bioinformatics and high-throughput cell-based screening assays to isolate novel factors involved in T cell biology. A ubiquitously expressed 98 kDa glycoprotein, ITFG1 contains an N-terminal signal peptide and a C-terminal transmembrane domain flanking twelve potential N-linked glycosylation sites. Human and mouse T cells treated with ITFG1 in vitro secreted the cytokines IFN-g, TNF-a and IL-10, while in vivo ITFG1 was protective in a mouse acute graft-versus-host disease (GVHD) model. Over amino acids (aa) 1-566, human ITFG1 shares 89% and 88% aa identity with mouse and rat ITFG1, respectively.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
product targets : Hedgehog inhibitors