s12963-016-0078-0

TSPAN1 Antibody (819202) [Alexa Fluor® 594] Summary

    Immunogen
    Mouse myeloma cell line NS0-derived recombinant human TSPAN1
    Met1-Gln241
    Accession # O60635
    Specificity
    Detects human TSPAN1 in direct ELISAs.
    Isotype
    IgG3
    Clonality
    Monoclonal
    Host
    Mouse
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Applications/Dilutions

    Dilutions
        Flow Cytometry 0.25-1 ug/10^6 cells

Packaging, Storage & Formulations

    Storage
    Store the unopened product at 2 – 8 °C. Do not use past expiration date.
    Buffer
    Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for TSPAN1 Antibody (819202) [Alexa Fluor® 594]

      NET1
      NET-1
      tetraspan 1
      Tetraspan NET-1
      tetraspanin 1
      Tetraspanin TM4-C
      tetraspanin-1
      TM4C
      TM4SF
      TSPAN1
      TSPAN-1

Background

Tetraspanins (TSPAN family) are small integral proteins that contain four transmembrane domains with two different and well characterized extracellular domains. Tetraspanins are found on the plasma membrane and within various intracellular organelles and granules in nearly all cell and tissue types. They interact with one another and with other transmembrane molecules, including integrins, generating a ‘web of interactions believed to control cell and membrane trafficking and compartmentalization. Tetraspanin-1 (TSPAN1), a 241 amino acid protein, interacts with the thiamine transporter-1 (THTR-1, SLC19A2) in human intestinal epithelial cells, linking TSPAN1 to the regulation of thiamine uptake. TSPAN1 has been found to be expressed in gastric, ovarian, colon, and other carcinomas.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

product targets : PERK inhibitors

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