Product Name :
Rabbit anti-PRKCQ Polyclonal Antibody
Synonym :
nPKC-theta; PRKCT
Host :
Rabbit
Species Reactivity:
Human, Mouse, Rat
Specificity :
Predicted Reactivity:
Applications :
WB 1:500 – 1:2000IHC 1:50 – 1:200
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human PRKCQ (NP_006248.1).
Concentration :
Purification :
Affinity purification
Clonality:
Polyclonal Antibody
Storage Temp.:
Store at -20 ℃Avoid freeze / that cycles
Research areas :
Background :
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role. The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipid-dependent protein kinase. This kinase is important for T-cell activation. It is required for the activation of the transcription factors NF-kappaB and AP-1, and may link the T cell receptor (TCR) signaling complex to the activation of the transcription factors.
UniProt :
Q04759
Additional information:
Product Details FAQ Citations(1) Video Pictures Documents |Overview |Synonym nPKC-theta; PRKCT |Host Rabbit |Species Reactivity Human, Mouse, Rat |Applications WB 1:500 – 1:2000IHC 1:50 – 1:200 |Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human PRKCQ (NP_006248.1). |Positive control HepG2,Rat testis |Properties |Purification Affinity purification |Clonality Polyclonal Antibody |Isotype IgG |Storage Temp. Store at -20 ℃Avoid freeze / that cycles |Storage Buffer Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |Target |Background Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role. The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipid-dependent protein kinase. This kinase is important for T-cell activation. It is required for the activation of the transcription factors NF-kappaB and AP-1, and may link the T cell receptor (TCR) signaling complex to the activation of the transcription factors. |Cellular localization Cell membrane,Cytoplasm,Peripheral membrane protein |UniProt Q04759 |Tips:This product is for research use only. Not for use in diagnostic prodcedures.
Rabbit anti-PRKCQ Polyclonal Antibody
Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.Related websites: https://www.medchemexpress.com/antibodies.html
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