s12981-015-0074-7

TCAP Antibody (2B1) Summary

    Immunogen
    TCAP (AAH12628, 1 a.a. – 167 a.a.) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MATSELSCEVSEENCERREAFWAEWKDLTLSTRPEEGCSLHEEDTQRHETYHQQGQCQVLVQRSPWLMMRMGILGRGLQEYQLPYQRVLPLPIFTPAKMGATKEEREDTPIQLQELLALETALGGQCVDRQEVAEITKQLPPVVPVSKPGALRRSLSRSMSQEAQRG
    Specificity
    TCAP – titin-cap (telethonin)
    Isotype
    IgG1 Kappa
    Clonality
    Monoclonal
    Host
    Mouse
    Gene
    TCAP
    Purity
    IgG purified
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Applications/Dilutions

    Dilutions
        ELISA
    Application Notes
    Antibody reactivity against recombinant protein on ELISA.

Packaging, Storage & Formulations

    Storage
    Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
    Buffer
    PBS (pH 7.4)
    Preservative
    No Preservative
    Purity
    IgG purified

Notes

Quality control test: Antibody Reactive Against Recombinant Protein.

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for TCAP Antibody (2B1)

      19 kDa sarcomeric protein
      CMD1NTitin cap protein
      LGMD2G
      limb girdle muscular dystrophy 2G (autosomal recessive)
      T-cap
      TELE
      telethonin
      titin-cap (telethonin)

Background

Sarcomere assembly is regulated by the muscle protein titin. Titin is a giant elastic protein with kinase activity that extends half the length of a sarcomere. It serves as a scaffold to which myofibrils and other muscle related proteins are attached. This gene encodes a protein found in striated and cardiac muscle that binds to the titin Z1-Z2 domains and is a substrate of titin kinase, interactions thought to be critical to sarcomere assembly. Mutations in this gene are associated with limb-girdle muscular dystrophy type 2G.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Simeprevir

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