s13293-015-0035-9

Pax3 Antibody (3A8) Summary

    Immunogen
    PAX3 (NP_852122 307 a.a. – 414 a.a.) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. LSETSYQPTSIPQAVSDPSSTVHRPQPLPPSTVHQSTIPSNPDSSSAYCLPSTRHGFSSYTDSFVPPSGPSNPMNPTIGNGLSPQVMGLLTNHGGVPHQPQTDYALSP
    Specificity
    PAX3 (3A8)
    Isotype
    IgG2b Kappa
    Clonality
    Monoclonal
    Host
    Mouse
    Gene
    PAX3
    Purity
    IgG purified
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Applications/Dilutions

    Dilutions
        Western Blot
        ELISA
    Application Notes
    Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB. GST tag alone is used as a negative control.

Packaging, Storage & Formulations

    Storage
    Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
    Buffer
    PBS (pH 7.4)
    Preservative
    No Preservative
    Purity
    IgG purified

Notes

Quality control test: Antibody Reactive Against Recombinant Protein.

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Pax3 Antibody (3A8)

      CDHS
      HUP2
      HUP2MGC120384
      MGC120381
      MGC120382
      MGC120383
      MGC134778
      paired box 3
      paired box gene 3 (Waardenburg syndrome 1)
      paired box homeotic gene 3
      paired box protein Pax-3
      paired domain gene 3
      paired domain gene HuP2
      Pax3
      Waardenburg syndrome 1
      WS1
      WS3

Background

This gene is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t(2;13)(q35;q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma. Alternative splicing results in transcripts encoding isoforms with different C-termini.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

product targets : Haspin Kinase inhibitors

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