s13046-016-0325-z

IL-17F Antibody (1058A) [Alexa Fluor® 750] Summary

    Additional Information
    Recombinant Monoclonal Antibody.
    Immunogen
    E.coli-derived recombinant mouse IL-17F
    Ala21-Val153
    Accession # Q7TNI7
    Specificity
    Detects mouse IL-17F in direct ELISAs.
    Isotype
    IgG
    Clonality
    Monoclonal
    Host
    Rabbit
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Applications/Dilutions

    Dilutions
        Intracellular Staining by Flow Cytometry 0.25-1 ug/10^6 cells

Packaging, Storage & Formulations

    Storage
    Store the unopened product at 2 – 8 °C. Do not use past expiration date.
    Buffer
    Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for IL-17F Antibody (1058A) [Alexa Fluor® 750]

      Cytokine ML-1
      IL17F
      IL-17F
      IL-17Finterleukin-17F
      IL24
      IL-24
      interleukin 17F
      Interleukin-24
      ML-1
      ML1interleukin-24

Background

IL-17F, also called ML-1 or IL-24, is one of six IL-17 family members.  All are homodimeric glycoproteins with conserved cysteines that form a cystine knot structure.  IL-17F is a 44 kDa dimer expressed by activated monocytes that acts in a stimulation loop with activated CD4+T cells to produce IL-2, TGFb and MCP-1.  Like IL-17A, it recruits neutrophils to airways during allergic reactions. IL-17F has a long form and a short form (predominant), which have alternate start sites but similar function. Mouse IL-17F is 58% aa identical to human IL-17F.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

product targets : AChE inhibitors

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