S1P2/EDG-5/S1PR2 Antibody (368510) [Alexa Fluor® 405] Summary
NS0 mouse myeloma cell line transfected with human S1P2/EDG-5
Met1-Val353
Accession # AAC98919
Met1-Val353
Accession # AAC98919
Detects human S1P2/EDG-5. Stains human S1P2/EDG-5 transfectants but not irrelevant transfectants.
IgG1
Monoclonal
Mouse
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Applications/Dilutions
- Flow Cytometry 0.25-1 ug/10^6 cells
Packaging, Storage & Formulations
Store the unopened product at 2 – 8 °C. Do not use past expiration date.
Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.
Notes
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for S1P2/EDG-5/S1PR2 Antibody (368510) [Alexa Fluor® 405]
- AGR16
- EDG5
- EDG-5
- endothelial differentiation G-protein coupled receptor 5
- endothelial differentiation, sphingolipid G-protein-coupled receptor, 5
- GPCR13
- GPCR18
- H218
- LPB2
- S1P receptor 2
- S1P receptor EDG5
- S1P receptor Edg-5
- S1P2
- S1PR2
- sphingosine 1-phosphate receptor 2
- sphingosine 1-phosphate receptor Edg-5
- sphingosine-1-phosphate receptor 2
Background
S1P2 (sphingosine 1-phosphate receptor-2), also known as EDG-5 (endothelial differentiation, G-protein coupled receptor-5), is a353 amino acid (aa) seven-transmembrane receptor putative glycoproteinthat binds the lysolipid phosphoric acid mediator, sphingosine1-phosphate. Extracellular portions of human S1P2 show 82.5% aaidentity with mouse S1P2 and 92% aa identity with human EDG-3, themost closely related family member. Both are expressed predominantly inthe lung, heart, kidney, liver, spleen, thymus, testis and brain,mediating both mitogenic and anti-apoptotic effects.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
product targets : Bcr-Abl inhibitors