ATG7 Antibody (683906) [Alexa Fluor® 750] Summary
E. coli-derived recombinant human ATG7
Asn387-Gln570
Accession # O95352
Asn387-Gln570
Accession # O95352
Detects human ATG7 in direct ELISAs and Western blots.In direct ELISAs and Western blots, nocross-reactivity with recombinant human ATG3, 4A, 4B, 5, 10, 12, or 16L1 isobserved.
N/A
IgG1
Monoclonal
Mouse
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Applications/Dilutions
- Intracellular Staining by Flow Cytometry 0.25-1 ug/10^6 cells
Packaging, Storage & Formulations
- 12 months from date of receipt, 2 to 8 °C as supplied.
Protect from light. Do not freeze.
Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.
Notes
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for ATG7 Antibody (683906) [Alexa Fluor® 750]
- APG7 autophagy 7-like (S. cerevisiae)
- APG7
- APG7L
- APG7-LIKE
- ATG12-activating enzyme E1 ATG7
- ATG7 autophagy related 7 homolog (S. cerevisiae)
- ATG7
- Autophagy-related protein 7
- DKFZp434N0735
- GSA7
- hAGP7
- ubiquitin activating enzyme E1-like protein
- Ubiquitin-activating enzyme E1-like protein
- ubiquitin-like modifier-activating enzyme ATG7
Background
ATG7, also known as APG7, is a 78 kDa cytosolic ubiquitin-E1-like enzyme that plays a key role in the autophagic pathway of intracellular bulk degradation. It is required for the conjugation of ATG5 to ATG12, the lipidation of ATG8, and subsequent autophagosome formation. ATG7 is required for mitochondrial removal during erythropoiesis and for the maintenance of axonal homeostasis. Alternate splicing of human ATG7 generates an isoform that lacks 31 aa at the C-terminus, a region that is required for ATG8 lipidation. Human ATG7 shares 93% aa sequence identitiy with mouse and rat ATG7.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
product targets : FAK inhibitors