g3.116.027508

CD133 Antibody (170411) [Alexa Fluor® 594] Summary

    Immunogen
    NS0 mouse myeloma cell line transfected with human CD133
    Accession # O43490
    Specificity
    Detects human CD133.
    Isotype
    IgG2a
    Clonality
    Monoclonal
    Host
    Mouse
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Applications/Dilutions

    Dilutions
        Flow Cytometry 0.25-1 ug/10^6 cells

Packaging, Storage & Formulations

    Storage
    Store the unopened product at 2 – 8 °C. Do not use past expiration date.
    Buffer
    Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for CD133 Antibody (170411) [Alexa Fluor® 594]

      AC133 Stargardt disease 4 (autosomal dominant)
      AC133
      CD133 retinal 2
      CD133
      PROM1
      prominin (mouse)-like 1
      Prominin 1
      PROML1

Background

CD133 antigen also known as prominin-1 is a glycoprotein that in humans is encoded by the PROM1 gene. It is a pentaspan transmembrane glycoprotein, with highly restricted expression on plasma membrane protrusions of epithelial and other cell types.  CD133 is expressed in hematopoietic stem cells, endothelial progenitor cells, glioblastoma, neuronal and glial stem cells, as well as adult kidney, mammary glands, trachea, salivary glands, placenta, digestive tract, and testes. CD133 is used as a main marker for hematopoietic stem cells in transplant models. It has also been described as a marker of tumor initiating cells. 

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

product targets : GPCR30 inhibitors

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