Glut4 Antibody (925932) [Alexa Fluor® 488] Summary
Mouse myeloma cell line NS0-derived recombinant human Glut4
Met1-Asp509
Accession # P14672
Met1-Asp509
Accession # P14672
Detects human Glut4 in direct ELISAs.
IgG2b
Monoclonal
Mouse
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Applications/Dilutions
- Flow Cytometry 0.25-1 ug/10^6 cells
Packaging, Storage & Formulations
Store the unopened product at 2 – 8 °C. Do not use past expiration date.
Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.
Notes
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for Glut4 Antibody (925932) [Alexa Fluor® 488]
- Glut4
- GLUT-4
- GLUT4Glucose transporter type 4, insulin-responsive
- insulin-responsive glucose transporter type 4
- SLC2A4
- solute carrier family 2 (facilitated glucose transporter), member 4
- solute carrier family 2, facilitated glucose transporter member 4
Background
Glut4 (Glucose Transporter Member 4), also known as SLC2A4, is a 509 aa multi-pass type membrane protein and shares 65% aa identity with mouse Glut4. It is an insulin-regulated glucose transporter. Glut4 is most highly expressed in adipose and striated muscle tissues, but has also been reported in multiple other tissues including the nervous system and breast cancer. Insulin stimulated transport of Glut4 has been shown to be impaired in type 2 diabetes patients. Additionally, inhibition of Glut4 may be useful in reducing proliferation of breast cancer cells.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
product targets : Cytoskeleton inhibitors