fnagi.2017.00018

p70 S6 Kinase/S6K Overexpression Lysate (Denatured) Summary

    Description
    Pasmid: pCMV-RPS6KB1 full-length
    Gene
    RPS6KB1

Packaging, Storage & Formulations

    Storage
    Store at -80C. Avoid freeze-thaw cycles.
    Buffer
    Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, and 0.01% Bromophenol blue).

Lysate Details for p70 S6 Kinase/S6K

    Type
    Overexpression
    Protein State
    Denatured

Notes

Quality control test: Transient overexpression cell lysate was tested with Anti-RPS6KB1 antibody by Western Blots.

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for p70 S6 Kinase/S6K Overexpression Lysate (Denatured)

      EC 2.7.11
      EC 2.7.11.1
      p70 ribosomal S6 kinase alpha
      p70 S6 kinase alpha
      p70 S6 Kinase
      p70 S6 kinase, alpha 1,70 kDa ribosomal protein S6 kinase 1
      p70 S6 kinase, alpha 2
      p70 S6KA
      p70 S6K-alpha
      p70(S6K)-alpha
      p70-alpha
      p70-S6K
      P70S6K1
      PS6K
      ribosomal protein S6 kinase beta-1
      Ribosomal protein S6 kinase I
      ribosomal protein S6 kinase, 70kD, polypeptide 1
      ribosomal protein S6 kinase, 70kDa, polypeptide 1
      RPS6KB1
      S6K
      S6K1
      S6K1p70-S6K 1
      S6K-beta-1
      serine/threonine kinase 14 alpha
      Serine/threonine-protein kinase 14A
      STK14A

Background

This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates several residues of the S6 ribosomal protein. The kinase activity of this protein leads to an increase in protein synthesis and cell proliferation. Amplification of the region of DNA encoding this gene and overexpression of this kinase are seen in some breast cancer cell lines. Alternate translational start sites have been described and alternate transcriptional splice variants have been observed but have not been thoroughly characterized. [provided by RefSeq]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Lysates are guaranteed for 6 months from date of receipt.

Methylnaltrexone (Bromide)

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