p53 [p Ser315] Antibody (FPS315) Summary
Synthetic peptide corresponding to a portion of human p53 phosphorylated at Ser315.
p Ser315
IgG1
Monoclonal
Mouse
TP53
Protein A purified
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Applications/Dilutions
- Western Blot 5 ug/ml
Reactivity Notes
Human
Packaging, Storage & Formulations
Store at -20C. Avoid freeze-thaw cycles.
PBS (pH 7.2) and 50% Glycerol
No Preservative
Protein A purified
Alternate Names for p53 [p Ser315] Antibody (FPS315)
- Antigen NY-CO-13
- BCC7
- FLJ92943
- LFS1
- LFS1TRP53
- p53 tumor suppressor
- p53
- P53cellular tumor antigen p53
- Phosphoprotein p53
- TP53
- transformation-related protein 53
- TRP53
- tumor protein p53
- Tumor suppressor p53
Background
p53 is a tumor suppressor gene expressed in a wide variety of tissue types and is involved in regulating cell growth, replication, and apoptosis. It binds to Mdm2, SV40 T antigen and human Papilloma virus E6 protein. p53 senses DNA damage and facilitates its repair. Mutation involving p53 is found in a wide variety of malignant tumors, including breast, ovary, bladder, colon, lung, and melanoma.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.