mGluR2 Antibody (3H7) Summary
GRM2 (NP_000830 414 a.a. – 506 a.a.) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. NGRRLYKDFVLNVKFDAPFRPADTHNEVRFDRFGDGIGRYNIFTYLRAGSGRYRYQKVGYWAEGLTLDTSLIPWASPSAGPLAASRCSEPCLQ
glutamate receptor, metabotropic 2
IgG2a Kappa
Monoclonal
Mouse
GRM2
IgG purified
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Applications/Dilutions
- ELISA
Antibody reactivity against recombinant protein on ELISA. GST alone used as a negative control.
Packaging, Storage & Formulations
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
PBS (pH 7.4)
No Preservative
IgG purified
Notes
Quality control test: Antibody Reactive Against Recombinant Protein.
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for mGluR2 Antibody (3H7)
- GLUR2
- glutamate metabotropic receptor 2
- glutamate receptor, metabotropic 2
- GPRC1B
- GPRC1Bmetabotropic glutamate receptor 2
- GRM2
- mGlu2
- mGluR2
- MGLUR2glutamate receptor homolog
- mGluR7
Background
L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.