hCG holo C2 Antibody (INN-hCG-53) Summary
Made to Human hCG holo C2
Secreted
NB100-63167 recognises epitope c2 on hCG holo C2. It does not recognise free hCG subunits.
IgG1
Monoclonal
Mouse
CGB
Protein A or G purified
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Applications/Dilutions
- Western Blot 1:100-1:2000
- ELISA 1:100-1:2000
Packaging, Storage & Formulations
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
PBS (pH 7.2)
0.09% Sodium Azide
1.0 mg/ml
Protein A or G purified
Alternate Names for hCG holo C2 Antibody (INN-hCG-53)
- choriogonadotropin subunit beta
- CGB3
- CGB5
- CGB7
- CGB8
- chorionic gonadotropin, beta polypeptide
- hCGB
Background
Human chorionic gonadotropin (hCG) is a glycoprotein hormone produced by trophoblastic cells of the placenta beginning 10 to 12 days after conception. Maintenance of the fetus in the first trimester of pregnancy requires the production of hCG, which binds to the corpus luteum of the ovary which is stimulated to produce progesterone which in turn maintains the secretory endometrium. hCG is present only in trace amounts in non pregnant urine and sera. It rises sharply during pregnancy. HCG is composed of two non identical, non covalently linked polypeptide chains designated as the a and b subunits. The a subunit of HCG is nearly identical to that of thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH) and luteinizing hormone (LH). A germ cell tumor which is positive for cytokeratin, placental alkaline phosphatase (PLAP) and HCG but negative for EMA and AFP is probably a choriocarcinoma.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.