c-Myc Antibody (9E10) [Alexa Fluor® 750] Summary
C-terminal region peptide of human c-Myc
Ala408-Ala439
Accession # P01106
Ala408-Ala439
Accession # P01106
Detects endogenous human c-Myc and c-Myc tagged proteins in Western blots.
N/A
IgG1
Monoclonal
Mouse
MYC
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Applications/Dilutions
- Intracellular Staining by Flow Cytometry 0.25-1 ug/10^6 cells
Flow Cytometry: Please use 0.25-1 ug of conjugated antibody per 10e6 cells.
Packaging, Storage & Formulations
- 12 months from date of receipt, 2 to 8 °C as supplied.
Protect from light. Do not freeze.
Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.
0.09% Sodium Azide
Please see the vial label for concentration. If unlisted please contact technical services.
Notes
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for c-Myc Antibody (9E10) [Alexa Fluor® 750]
- avian myelocytomatosis viral oncogene homolog
- BHLHE39
- bHLHe39MRTL
- Class E basic helix-loop-helix protein 39
- cMyc
- c-Myc
- myc proto-oncogene protein
- Myc
- Myc2
- MYCC
- myc-related translation/localization regulatory factor
- Niard
- Nird
- Proto-oncogene c-Myc
- Transcription factor p64
- v-myc avian myelocytomatosis viral oncogene homolog
- v-myc myelocytomatosis viral oncogene homolog (avian)
Background
Human c-Myc is a helix-loop-helix transcription factor which efficiently binds DNA after heterodimerization with the bHLH protein Max. It is often overexpressed and mutated in hematopoietic tumors. Mutations frequently result in truncation around amino acid (aa) 252, before the C-terminal DNA binding, HLH and leucine zipper domains. The 439 aa human c-Myc has one O-glycosylation site and has three Ser/Thr phosphorylation sites near the N-terminus. Human c-Myc shows 92% aa identity with mouse or rat c-Myc.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.