beta 2 Microglobulin, H-2Dd antigen Antibody (D1) Summary
Made to Mouse MHC CLASS I H-2Dd
Recognizes the H-2Dd determinant of mouse MHC Class I.
IgG2a
Monoclonal
Mouse
B2M
Tissue culture supernatant
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Applications/Dilutions
- Flow Cytometry Neat
For Flow Cytometry: Use 10 ul of suggested dilution to label 10^6 cells in 100 ul.
Reactivity Notes
Reacts with Mouse. Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Additional Mouse on Mouse blocking steps may be required for IHC and ICC experiments. Please contact Technical Support for more information.
Packaging, Storage & Formulations
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
No buffer
0.09% Sodium Azide
Tissue culture supernatant
Alternate Names for beta 2 Microglobulin, H-2Dd antigen Antibody (D1)
- beta chain of MHC class I molecules
- beta-2-microglobin
- beta-2-microglobulin
Background
MHC Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. MHC class I antigens are heterodimers consisting of one alpha chain (44kDa) with beta 2 microglobulin (11.5 kDa). The antigen is expressed by all somatic cells at varying levels. MHC Class I molecules are expressed on most nucleated cells where they present endogenously synthesized antigenic peptides to CD8+ T lymphocytes, which are usually cytotoxic T cells. Fibroblasts or neurons however only show a low level of antigen.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.