XPE/DDB2 Antibody (1F11) Summary
DDB2 (AAH00093, 1 a.a. – 109 a.a.) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MAPKKRPETQKTSEIVLRPRNKRSRSPLELEPEAKKLCAKGSGPSRRCDSDCLWVGLAGPQILPPCRSIVRTLHQHKLGRASWPSVQQGLQQSFLHTLDSYRILQKAAP
Reacts with damage-specific DNA binding protein 2, 48kDa.
IgG2b Kappa
Monoclonal
Mouse
DDB2
Protein A purified
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Applications/Dilutions
- Western Blot
- ELISA
This antibody is reactive against recombinant protein in WB and ELISA.
Packaging, Storage & Formulations
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
PBS (pH 7.4)
No Preservative
Protein A purified
Notes
Quality control test: Antibody Reactive Against Recombinant Protein.
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for XPE/DDB2 Antibody (1F11)
- damage-specific DNA binding protein 2 (48kD)
- damage-specific DNA binding protein 2, 48kDa
- Damage-specific DNA-binding protein 2
- DDB p48 subunit
- DDB2
- DDBB
- DNA damage-binding protein 2
- FLJ34321
- UV-damaged DNA-binding protein 2
- UV-DDB 2
- UV-DDB2
- xeroderma pigmentosum group E protein
- XP5
- XPE/DDB2
Background
This gene encodes a protein that is necessary for the repair of ultraviolet light-damaged DNA. This protein is the smaller subunit of a heterodimeric protein complex that participates in nucleotide excision repair, and this complex mediates the ubiquitylation of histones H3 and H4, which facilitates the cellular response to DNA damage. This subunit appears to be required for DNA binding. Mutations in this gene cause xeroderma pigmentosum complementation group E, a recessive disease that is characterized by an increased sensitivity to UV light and a high predisposition for skin cancer development, in some cases accompanied by neurological abnormalities. [provided by RefSeq]
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
product targets :　PAI-2 inhibitors