Wnt-5b Antibody Summary
Synthetic 14 amino acid peptide from internal region of human WNT5B.
internal domain of human
Human WNT5B. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Monkey (100%), Primate (93%). Backed by our 100% Guarantee.
IgG
Polyclonal
Rabbit
WNT5B
Immunogen affinity purified
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Applications/Dilutions
- Immunohistochemistry-Paraffin 5 ug/ml
Reactivity Notes
Predicted cross-reactivity based on sequence identity: Orangutan (100%), Gibbon (100%), Gorilla (93%), Marmoset (93%), Canine (86%), Elephant (86%), Equine (86%), Rabbit (86%), Opossum (86%).
Packaging, Storage & Formulations
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
PBS
0.1% Sodium Azide
1.0 mg/ml
Immunogen affinity purified
Alternate Names for Wnt-5b Antibody
- MGC2648
- protein Wnt-5b
- wingless-type MMTV integration site family, member 5B
- WNT-5B protein
- Wnt5b
- Wnt-5b
Background
WNT5B is a ligand for members of the frizzled family of seven transmembrane receptors. Wnt proteins constitute a large family of secreted molecules that are involved in intercellular signalling during development and have been implicated in oncogenesis. Very little is known about the structure of Wnts as they are notoriously insoluble; but they share the following features characteristics of secretory proteins: a signal peptide, several potential N-glycosylation sites and 22 conserved cysteines. The Wnt proteins seem to adhere to the plasma membrane of the secreting cells and are therefore likely to signal over only few cell diameters. Fifteen major Wnt gene families have been identified in vertebrates, with multiple subtypes within some classes.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.