srep17921

USP33 Antibody Summary

    Immunogen
    Synthetic 14 amino acid peptide from internal region of human USP33.
    Epitope
    internal domain of human protein
    Specificity
    Human USP33. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
    Predicted Species
    Monkey (93%). Backed by our 100% Guarantee.
    Isotype
    IgG
    Clonality
    Polyclonal
    Host
    Rabbit
    Gene
    USP33
    Purity
    Immunogen affinity purified
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Applications/Dilutions

    Dilutions
        Immunohistochemistry-Paraffin 5 ug/ml

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Orangutan (86%), Gibbon (86%), Marmoset (86%), Canine (86%), Bovine (86%), Panda (86%).

Packaging, Storage & Formulations

    Storage
    Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
    Buffer
    PBS
    Preservative
    0.1% Sodium Azide
    Concentration
    1.0 mg/ml
    Purity
    Immunogen affinity purified

Alternate Names for USP33 Antibody

      Deubiquitinating enzyme 33
      EC 3.1.2.15
      EC 3.4.19.12
      hVDU1
      KIAA1097MGC16868
      pVHL-interacting deubiquitinating enzyme 1
      ubiquitin carboxyl-terminal hydrolase 33
      ubiquitin specific peptidase 33
      ubiquitin thioesterase 33
      Ubiquitin thiolesterase 33
      Ubiquitin-specific-processing protease 33
      VDU1ubiquitin specific protease 33
      VHL-interacting deubiquitinating enzyme 1

Background

The ubiquitin dependent protein degradation pathway is essential for the proteolysis of intracellular proteins and peptides. Deubiquitination, is catalyzed by proteases called deubiquitinating enzymes. USP33 is a deubiquitinating enzyme that binds to the von Hippel-Lindau tumor suppressor protein. It also regulates thyroid hormone activation by deubiquitinating type 2 iodothyronine deiodinase.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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