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Twist-1 Antibody Summary

    Immunogen
    TWIST1 (NP_000465, 100 a.a. – 202 a.a.) partial recombinant protein with GST tag. PQSYEELQTQRVMANVRERQRTQSLNEAFAALRKIIPTLPSDKLSKIQTLKLAARYIDFLYQVLQSDELDSKMASCSYVAHERLSYAFSVWRMEGAWSMSASH
    Specificity
    TWIST1 – twist homolog 1 (acrocephalosyndactyly 3; Saethre-Chotzen syndrome) (Drosophila)
    Isotype
    IgG
    Clonality
    Polyclonal
    Host
    Mouse
    Gene
    TWIST1
    Purity
    Unpurified
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Applications/Dilutions

    Dilutions
        Western Blot
        ELISA
    Application Notes
    The quality control of this antibody is limited to WB on the immunizing protein. It has been used for ELISA. Abnovas recommended working dilutions for western analysis are as follows: 1:500 dilution for ascites 1:1000 for purified Ig 1:500

Packaging, Storage & Formulations

    Storage
    Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
    Buffer
    Whole antisera with 50% Glycerol
    Preservative
    No Preservative
    Purity
    Unpurified

Notes

Quality control test: Antibody Reactive Against Recombinant Protein.

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Twist-1 Antibody

      acrocephalosyndactyly 3
      ACS3
      B-HLH DNA binding protein
      BHLHA38
      bHLHa38BPES3
      BPES3
      Class A basic helix-loop-helix protein 38
      CRS1
      H-twist
      H-twistblepharophimosis, epicanthus inversus and ptosis 3
      SCSBPES2
      twist homolog 1 (Drosophila)
      TWIST homolog of drosophila
      TWIST
      Twist1
      Twist-1
      twist-related protein 1

Background

Basic helix-loop-helix (bHLH) transcription factors have been implicated in cell lineage determination and differentiation. The protein encoded by this gene is a bHLH transcription factor and shares similarity with another bHLH transcription factor, Dermo1. The strongest expression of this mRNA is in placental tissue; in adults, mesodermally derived tissues express this mRNA preferentially. Mutations in this gene have been found in patients with Saethre-Chotzen syndrome.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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