Thyroid Peroxidase Antibody (TPO35) Summary
Hybridoma clone has been derived from hybridization of Sp2/0 myeloma cells with spleen cells of Balb/c mice immunized with human thyroid peroxidase.
IgG1
Monoclonal
Mouse
TPO
Protein A purified
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Applications/Dilutions
- Immunoassay
- Sandwich ELISA 1:100-1:2000
Works in direct ELISA and sandwich immunoassays. Recommended pairs for sandwichimmunoassays (capture-detection): NBP1-50811 – NBP1-50813, NBP1-50812 – NBP1-50813
Reactivity Notes
Human
Packaging, Storage & Formulations
Store at 4C. Do not freeze.
PBS (pH 7.4)
0.09% Sodium Azide
Protein A purified
Alternate Names for Thyroid Peroxidase Antibody (TPO35)
- EC 1.11.1
- MSA
- TDH2A
- thyroid microsomal antigen
- thyroid peroxidase
- thyroperoxidase
- TPXEC 1.11.1.8
Background
Thyroid Peroxidase (TPO) plays a central role in thyroid gland function. The enzyme catalyzes two important reactions of thyroid hormone synthesis: the iodination of tyrosine residues in thyroglobulin and phenoxy ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. A defect in this gene is thought to cause several disorders of thyroid hormonogenesis.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
product targets : Filovirus inhibitors