TLR4 Antibody (HTA125) [PE] Summary
Ba/F3 cell line expressing TLR4
Type I membrane protein.
NB600-662 recognizes the human Toll like receptor 4 (TLR4) cell surface antigen. TLR4, also known as CD284, has been demonstrated to act as a receptor for LPS on human monocytes and macrophages. TLR4 signalling of LPS stimulation requires the presence of the MD-2 molecule. TLR4 is weakly expressed by resting cells, but is upregulated following stimulation with LPS. This antibody has been demonstrated to block activation of monocytes with LPS.
IgG2a
Monoclonal
Mouse
TLR4
Protein A or G purified
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Applications/Dilutions
- Western Blot 1:100-1:2000
- Flow Cytometry 1:10-1:1000
- LPS from E. Coli, TLR4 ligand
- TLR4 Inhibitor Peptide Set
- TIRAP (TLR2 and TLR4) Inhibitor Peptide Set
Reactivity Notes
Cross-reacts with Human and Guinea Pig.Not yet tested in other species.
Packaging, Storage & Formulations
Store at 4C. Do not freeze.
PBS and 1.0% BSA
0.05% Sodium Azide
Protein A or G purified
Alternate Names for TLR4 Antibody (HTA125) [PE]
- ARMD10
- CD284 antigen
- CD284
- hTollhomolog of Drosophila toll
- TLR4
- TOLL
- toll-like receptor 4
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
product targets :　Immunology/Inflammation_Compound_Library inhibitors