srep17909

TGR5/GPBAR1 Antibody Summary

    Immunogen
    Synthetic 16 amino acid peptide from 1st cytoplasmic domain of human TGR5.
    Epitope
    1st cytoplasmic domain of human
    Specificity
    Human TGR5. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
    Predicted Species
    Equine (94%), Primate (100%), Monkey (94%), Rabbit (94%). Backed by our 100% Guarantee.
    Isotype
    IgG
    Clonality
    Polyclonal
    Host
    Rabbit
    Gene
    GPBAR1
    Purity
    Immunogen affinity purified
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Applications/Dilutions

    Dilutions
        Immunohistochemistry-Paraffin 18 ug/ml
    Positive Control TGR5/GPBAR1 Lysate (NBL1-11217)

Reactivity Notes

Predicted cross-reactivity based on seuqence identity: Gorilla (100%), Gibbon (100%), Marmoset (100%), Elephant (100%), Mouse (88%), Bat (88%), Bovine (88%), Hamster (88%), Rat (81%), Canine (81%), Opossum (81%).

Packaging, Storage & Formulations

    Storage
    Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
    Buffer
    PBS
    Preservative
    0.1% Sodium Azide
    Concentration
    1.0 mg/ml
    Purity
    Immunogen affinity purified

Alternate Names for TGR5/GPBAR1 Antibody

      BG37
      BG37hBG37
      G protein-coupled bile acid receptor 1
      GPBA
      GPBAR1
      GPCR19
      GPR131
      G-protein coupled bile acid receptor 1
      G-protein coupled bile acid receptor BG37
      G-protein coupled receptor GPCR19
      M-BAR
      M-BARhGPCR19
      membrane bile acid receptor
      Membrane-type receptor for bile acids
      MGC40597
      TGR5
      TGR5GPCR

Background

BG37/TGR5 is the first Bile Acid GPCR to be identified. BG37/TGR5 expression has been reported in a wide variety of tissues, especially placenta, spleen, and monocyte/macrophages. ESTs have been isolated from blood, breast, and skin libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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