TGF-beta RI/ALK-5 Antibody – Pre-diluted Summary
Synthetic peptide corresponding to internal region of human TGF beta R1.
This product is specific for Transforming Growth Factor R1
IgG
Polyclonal
Rabbit
TGFBR1
Immunogen affinity purified
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Applications/Dilutions
- Immunohistochemistry 1:10-1:500
- Immunohistochemistry-Paraffin Neat
This product is useful for Immunohistochemistry Paraffin. If a 6mL or 7mL pre-diluted size is purchased this product can be used Neat (without further dilution). Use recommended dilution for the concentrated vials only.
Reactivity Notes
This product is specific for Human.
Packaging, Storage & Formulations
Store at 4C. Do not freeze.
Prediluted antibody with 50mM Tris (pH 7.7) and 1.0% BSA
0.1% Sodium Azide
Immunogen affinity purified
Alternate Names for TGF-beta RI/ALK-5 Antibody – Pre-diluted
- AAT5
- activin A receptor type II-like kinase, 53kD
- activin A receptor type II-like kinase, 53kDa
- Activin receptor-like kinase 5
- ACVRLK4
- ALK-5
- ALK-5ALK5
- EC 2.7.11
- EC 2.7.11.30
- LDS1A
- LDS2A
- Serine/threonine-protein kinase receptor R4
- SKR4
- tbetaR-I
- TGFB1R1
- TGF-beta receptor type I
- TGF-beta receptor type-1
- TGF-beta RI
- TGF-beta type I receptor
- TGFbetaRI
- TGFBR1
- TGF-bRI
- TGFR-1
- transforming growth factor beta receptor I
- transforming growth factor, beta receptor 1
- transforming growth factor, beta receptor I (activin A receptor type II-likekinase, 53kD)
- Transforming growth factor-beta receptor type I
Background
Three members of the TGF beta family, TGF beta 1, TGF beta 2 and TGF beta 3, are known in mammals. TGF betas mediate their activity by high affinity binding to the type 2 receptor, which requires both its kinase activity and association with members of a series of related type 1 receptors called activin receptor like kinase (ALK) 1 to 6. Of these, only ALK5 has been shown to represent a functional TGF beta type 1 receptor, but only ALK2 and ALK4 bind activin with high affinity. TGF beta R3 binds TGF beta and retains TGF beta for presentation to the signaling receptors.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.