s11121-015-0620-5

TEM5/GPR124 Antibody (499716) [Alexa Fluor® 750] Summary

    Immunogen
    Chinese hamster ovary cell line CHO-derived recombinant human TEM5/GPR124
    Met1-Leu699
    Accession # Q96PE1
    Specificity
    Detects human TEM5/GPR124 in direct ELISAs.
    Isotype
    IgG2b
    Clonality
    Monoclonal
    Host
    Mouse
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Applications/Dilutions

    Dilutions
        Flow Cytometry 0.25-1 ug/10^6 cells

Packaging, Storage & Formulations

    Storage
    Store the unopened product at 2 – 8 °C. Do not use past expiration date.
    Buffer
    Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for TEM5/GPR124 Antibody (499716) [Alexa Fluor® 750]

      DKFZp434C211
      DKFZp434J0911
      G protein-coupled receptor 124
      GPR124
      G-protein coupled receptor 124
      KIAA1531
      KIAA1531FLJ14390
      TEM5
      TEM5Tumor endothelial marker 5

Background

G protein-coupled receptor 124 (GPR124, also known as TEM5), is a member of the adhesion family of G protein coupled receptors and is localized on the surface of endothelial cells. GPR124 is abundantly expressed in tumor vessels, heart, placenta, ovary, small intestine, and colon. This receptor mediates endothelial cell survival during angiogenesis by linking integrin to glycosaminoglycans. GPR124 has also been shown to interact with DLG1 through its PDZ-binding motif.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

THZ12

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