TDO2 Antibody (1C8) Summary

fpsyg.2015.01473

TDO2 Antibody (1C8) Summary

    Immunogen
    TDO2 (NP_005642 307 a.a. – 405 a.a.) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. PFQLLTSLMDIDSLMTKWRYNHVCMVHRMLGSKAGTGGSSGYHYLRSTVSDRYKVFVDLFNLSTYLIPRHWIPKMNPTIHKFLYTAEYCDSSYFSSDES
    Specificity
    TDO2 – tryptophan 2,3-dioxygenase
    Isotype
    IgG2a Kappa
    Clonality
    Monoclonal
    Host
    Mouse
    Gene
    TDO2
    Purity
    IgG purified
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Applications/Dilutions

    Dilutions
        ELISA
    Application Notes
    Antibody reactivity against recombinant protein on ELISA. GST alone used as a negative control.

Packaging, Storage & Formulations

    Storage
    Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
    Buffer
    PBS (pH 7.4)
    Preservative
    No Preservative
    Purity
    IgG purified

Notes

Quality control test: Antibody Reactive Against Recombinant Protein.

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for TDO2 Antibody (1C8)

      chky
      TDO
      TDO2
      TDOTO
      TO
      TPH2EC 1.13.11.11
      TRPO
      TRPOtryptophanase
      Tryptamin 2,3-dioxygenase
      tryptophan 2,3-dioxygenase
      Tryptophan Oxygenase
      Tryptophan Pyrrolase
      Tryptophanase

Background

Tryptophan hydroxylase is the rate-limiting enzyme in the synthesis of serotonin (5-hydroxytryptamine, or 5HT). 5HT is causally involved in numerous central nervous activities, and it has several functions in peripheral tissues, including the maintenance of vascular tone and gut motility. Incorporates oxygen into the indole moiety of tryptophan. Has a broad specificity towards tryptamine and derivatives including D- and L-tryptophan, 5-hydroxytryptophan and serotonin

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

product targets : (gamma)-secretase inhibitors