Somatostatin R2/SSTR2 Antibody Summary
Synthetic 16 amino acid peptide from C-terminus of human SSTR2.
Cell Membrane
Somatostatin Receptor Type 2
IgG
Polyclonal
Rabbit
SSTR2
Immunogen affinity purified
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Applications/Dilutions
- Immunohistochemistry-Paraffin 16 ug/ml
Reactivity Notes
Human
Packaging, Storage & Formulations
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
PBS
0.1% Sodium Azide
1.0 mg/ml
Immunogen affinity purified
Alternate Names for Somatostatin R2/SSTR2 Antibody
- Smstr2
- Somatostatin R2
- somatostatin receptor 2
- somatostatin receptor type 2
- SomatostatinR2
- SRIF-1
- SS2R
- SS-2-R
- SS2-R
- SST2
- SSTR2
Background
SST2 is a Somatostatin receptor. Somatostatin negatively regulates the growth of various normal and tumour cells via five somatostatin receptors. Somatostatin receptors are expressed by a large variety of human tumors, and the predominant expression of SST2 receptors in tumor tissues forms the basis for the successful application of SST2-preferring agonists in the treatment of patients with GH-secreting pituitary adenomas, as well as in patients with carcinoid or islet cell tumors. The SST2 receptor exists as two splice variants that differ in length and composition of their intracellular carboxy termini. SST2 is the only member of the somatostatin receptor family that contains introns. SST2 expression has been reported in adrenal, aorta, brain, breast, eye, gastrointestinal tract, pancreas, prostate, spinal cord, and thyroid. ESTs have been isolated from brain, eye, head/neck, kidney, lymph node, pineal, and prostate libraries.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.