STAT2 Antibody (1021D) [Alexa Fluor® 700] Summary
Recombinant Monoclonal Antibody.
Phosphopeptide containing the human STAT2 Y689 site
Detects human phospho-STAT2 (Y689) in direct ELISAs and Western blots.
IgG
Monoclonal
Rabbit
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Applications/Dilutions
- Intracellular Staining by Flow Cytometry 0.25-1 ug/10^6 cells
Packaging, Storage & Formulations
Store the unopened product at 2 – 8 °C. Do not use past expiration date.
Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.
Notes
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for STAT2 Antibody (1021D) [Alexa Fluor® 700]
- interferon alpha induced transcriptional activator
- ISGF-3
- MGC59816
- P113
- signal transducer and activator of transcription 2
- signal transducer and activator of transcription 2, 113kD
- signal transducer and activator of transcription 2, 113kDa
- STAT113
- STAT2
Background
STAT2 (signal transducer and activator of transcription 2) is a 113 kDa member of the STAT family of cytoplasmic transcription factors. STAT members generally mediate cytokine, growth factor and hormone receptor signal transduction. STAT2 is associated with type I ( alpha – and beta -) interferon signaling. All STATs contain an N‑terminal oligomerization domain, a DNA-binding domain, and an SH2-association region. STAT2 is phosphorylated at Y689 by receptor-associated Janus kinases (JAKs) leading to STAT2 dimerization and subsequent translocation to the nucleus to activate gene transcription.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.