SPG21 Antibody (2B11) Summary
SPG21 (NP_057714, 211 a.a. ~ 307 a.a) partial recombinant protein with GST tag.PHKIRDIPVTIMDVFDQSALSTEAKEEMYKLYPNARRAHLKTGGNFPYLCRSAEVNLYVQIHLLQFHGTKYAAIDPSMVSAEELEVQKGSLGISQE
SPG21 – spastic paraplegia 21 (autosomal recessive, Mast syndrome)
IgG2a Kappa
Monoclonal
Mouse
SPG21
IgG purified
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Applications/Dilutions
- ELISA
Antibody reactive against recombinant protein on ELISA.
Reactivity Notes
Human. Other species not tested.
Packaging, Storage & Formulations
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
PBS (pH 7.4)
No Preservative
IgG purified
Notes
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for SPG21 Antibody (2B11)
- Acid cluster protein 33
- ACP33Spastic paraplegia 21 protein
- GL010
- MASPARDIN
- MASTBM-019
- spastic paraplegia 21 (autosomal recessive, Mast syndrome)
- Spastic paraplegia 21 autosomal recessive Mast syndrome protein
Background
The protein encoded by this gene was identified by a two-hybrid screen using CD4 as the bait. It binds to the hydrophobic C-terminal amino acids of CD4 which are involved in repression of T cell activation. The interaction with CD4 is mediated by the noncatalytic alpha/beta hydrolase fold domain of this protein. It is thus proposed that this gene product modulates the stimulatory activity of CD4. At least three different transcript variants encoding two different isoforms have been found for this gene.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.