journal.pbio.1002339

SOX4 Antibody Summary

    Immunogen
    Synthetic peptide corresponding to internal region of human SOX4.
    Specificity
    This product is specific for SOX4
    Isotype
    IgG
    Clonality
    Polyclonal
    Host
    Rabbit
    Gene
    SOX4
    Purity
    Immunogen affinity purified
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Applications/Dilutions

    Dilutions
        Immunohistochemistry 1:10-1:500
        Immunohistochemistry-Paraffin 1:50

Reactivity Notes

This product is specific for Human.

Packaging, Storage & Formulations

    Storage
    Store at 4C. Do not freeze.
    Buffer
    10mM PBS (pH 7.4) and 1.0% BSA
    Preservative
    0.1% Sodium Azide
    Purity
    Immunogen affinity purified

Alternate Names for SOX4 Antibody

      ecotropic viral integration site 16
      EVI16
      SRY (sex determining region Y)-box 4
      SRY-related HMG-box gene 4
      transcription factor SOX-4

Background

This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins, such as syndecan binding protein (syntenin). The protein may function in the apoptosis pathway leading to cell death as well as to tumorigenesis and may mediate downstream effects of parathyroid hormone (PTH) and PTH-related protein (PTHrP) in bone development. The solution structure has been resolved for the HMG-box of a similar mouse protein.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Z-DEVD-FMK

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