jpts.27.3417

SMURF1 Antibody Summary

    Immunogen
    SMURF1 (NP_065162, 165 a.a. ~ 269 a.a) partial recombinant protein with GST tag.DSGPGRPLSCFMEEPAPYTDSTGAAAGGGNCRFVESPSQDQRLQAQRLRNPDVRGSLQTPQNRPHGHQSPELPEGYEQRTTVQGQVYFLHTQTGVSTWHDPRIP
    Specificity
    SMURF1 – SMAD specific E3 ubiquitin protein ligase 1
    Isotype
    IgG
    Clonality
    Polyclonal
    Host
    Mouse
    Gene
    SMURF1
    Purity
    Unpurified
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Applications/Dilutions

    Dilutions
        Western Blot 1:500
        ELISA
    Application Notes
    The quality control of this antibody is limited to Western blot on the immunizing protein. It has also been used for ELISA. Abnovas recommended working dilutions for western analysis are as follows: 1:500 dilution for ascites 1:1000 for purified Ig 1:500

Reactivity Notes

Human. Other species not tested.

Packaging, Storage & Formulations

    Storage
    Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
    Buffer
    50% Glycerol
    Preservative
    No Preservative
    Purity
    Unpurified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for SMURF1 Antibody

      E3 ubiquitin ligase SMURF1
      EC 6.3.2
      EC 6.3.2.-
      hSMURF1
      KIAA1625
      KIAA1625E3 ubiquitin-protein ligase SMURF1
      SMAD specific E3 ubiquitin protein ligase 1
      SMAD ubiquitination regulatory factor 1
      Smad-specific E3 ubiquitin ligase 1
      SMAD-specific E3 ubiquitin-protein ligase 1
      SMURF1

Background

This gene encodes a ubiquitin ligase that is specific for receptor-regulated SMAD proteins in the bone morphogenetic protein (BMP) pathway. A similar protein in Xenopus is involved in embryonic pattern formation. Alternative splicing results in multiple transcript variants encoding different isoforms. An additional transcript variant has been identified, but its full length sequence has not been determined.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Erastin

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