Renin Antibody (F32 VIII C4) Summary
Purified hog renin.
IgG1
Monoclonal
Mouse
REN
Unpurified
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Applications/Dilutions
- Western Blot 1:100-1:2000
Reactivity Notes
Pig
Packaging, Storage & Formulations
Store at 4C. Do not freeze.
Ascites
No Preservative
Unpurified
Notes
Relevant Entrez Gene Numbers: NM_000537.2
Alternate Names for Renin Antibody (F32 VIII C4)
- angiotensin-forming enzyme
- Angiotensinogenase
- EC 3.4.23
- EC 3.4.23.15
- FLJ10761
- HNFJ2
- REN
- renin precursor, renal
- Renin
Background
Renin is processed as a 406 amino acid precursor (45 kDa) containing a 23 amino acid signal peptide and a 43 amino acid propeptide that is released from renal juxtaglomerular cells in response to sodium depletion, decreased blood volume and blood pressure, and b-adrenergic stimulation. Renin initiates a sequence of steps that begins with cleavage of a decapeptide angiotensin I from renin substrate (angiotensinogen), an alpha-2-globulin produced in the liver (and other organs including the kidney.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.