Recombinant Mouse IL-17F Protein Summary
Recombinant bioactive protein containing 266 amino acids for Mouse IL-17F
Source:E. coli
Amino Acid Sequence:(Q7TNI7)
Method
>98% SDS-PAGE
IL-17F is fully bioactive when compared to standard. The ED50 as determined by the dose-dependent induction of IL-6 in NHDF is 1.94 ng/ml.
E. coli
Biologically Active Protein
IL17F
>95%, by SDS-PAGE
<0.1 ng/ug
Applications/Dilutions
29.8 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Packaging, Storage & Formulations
Store at -20 to -80C. Avoid freeze-thaw cycles.
Lyophilized with no additives
Lyoph
>95%, by SDS-PAGE
Reconstitute in sterile H2O to a concentration of 0.1 mg/ml (Note: Gently pipetting to dissolve). The solution can then be diluted into other aqueous buffers.
Alternate Names for Recombinant Mouse IL-17F Protein
- Cytokine ML-1
- IL17F
- IL-17F
- IL-17Finterleukin-17F
- IL24
- IL-24
- interleukin 17F
- Interleukin-24
- ML-1
- ML1interleukin-24
Background
Homodimeric interleukin-17F is a member of the IL-17 family of six homodimeric proteins (IL-17A-17F). Activated CD4+ T cells have also been shown to produce Mouse IL-17F. Activity studies reveal IL-17A to be the most potent, followed by IL-17A/F and IL-17F 100 fold lower than IL-17A. Recombinant Mouse IL-17F produced in E.Coli is a non-glycosylated polypeptide comprised of two monomeric subunit each of mIL-17F. The dimer consists of 266 amino acids, with an approximate molecular weight of 29.8 kDa.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 2 years from date of receipt.