ajim.22582

Recombinant Human eIF3K Protein Summary

    Description
    A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-218 of Human eIF3K

    Source: E.coli

    Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MAMFEQMRAN VGKLLKGIDR YNPENLATLE RYVETQAKEN AYDLEANLAV LKLYQFNPAF FQTTVTAQIL LKALTNLPHT DFTLCKCMID QAHQEERPIR QILYLGDLLE TCHFQAFWQA LDENMDLLEG ITGFEDSVRK FICHVVGITY QHIDRWLLAE MLGDLSDSQL KVWMSKYGWS ADESGQIFIC SQEESIKPKN IVEKIDFDSV SSIMASSQ

    Source
    E. coli
    Protein/Peptide Type
    Recombinant Protein
    Gene
    EIF3K
    Purity
    >95% pure by SDS-PAGE

Applications/Dilutions

    Theoretical MW
    27.2 kDa.
    Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

    Storage
    Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
    Buffer
    20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 0.1M NaCl, 1mM DTT
    Preservative
    No Preservative
    Concentration
    1 mg/ml
    Purity
    >95% pure by SDS-PAGE

Alternate Names for Recombinant Human eIF3K Protein

      ARG134
      eIF3k
      EIF3-p28
      EIF3S12eIF-3 p28
      Eukaryotic translation initiation factor 3 subunit 12
      eukaryotic translation initiation factor 3 subunit K
      eukaryotic translation initiation factor 3, subunit 12
      eukaryotic translation initiation factor 3, subunit K
      HSPC029
      M9
      MSTP001
      muscle specific
      Muscle-specific gene M9 protein
      PLAC24
      PLAC-24
      PLAC-24eIF-3 p25
      PRO1474
      PTD001

Background

EIF3K, also known as eukaryotic translation initiation factor 3 subunit K, belongs to the eIF3 subunit K family. It is the smallest subunit of eIF3 and it interacts with several other subunits of eIF3 and the 40S ribosomal subunit. This protein is conserved among high eukaryotes, including mammals, insects, and plants, and it is ubiquitously expressed in human tissues. It is distributed both in nucleus and cytoplasm and colocalizes with cyclin D3, a regulatory subunit of cyclin-dependent kinase 4 (Cdk4). Recombinant human EIF3K protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

product targets : STAT inhibitors

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