Recombinant Human TL1A/TNFSF15 Protein Summary
A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 72-251 of Human TL1A/TNFSF15
Source: E.coli
Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MLKGQEFAPS HQQVYAPLRA DGDKPRAHLT VVRQTPTQHF KNQFPALHWE HELGLAFTKN RMNYTNKFLL IPESGDYFIY SQVTFRGMTS ECSEIRQAGR PNKPDSITVV ITKVTDSYPE PTQLLMGTKS VCEVGSNWFQ PIYLGAMFSL QEGDKLMVNV SDISLVDYTK EDKTFFGAFL L
E. coli
Recombinant Protein
TNFSF15
>95% pure by SDS-PAGE
< 1.0 EU per 1 microgram of protein (determined by LAL method)
Applications/Dilutions
22.7 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Packaging, Storage & Formulations
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 50% glycerol, 0.2M NaCl
No Preservative
1 mg/ml
>95% pure by SDS-PAGE
Alternate Names for Recombinant Human TL1A/TNFSF15 Protein
- MGC129934
- MGC129935
- TL1A
- TL1Vascular endothelial cell growth inhibitor
- TNF superfamily ligand TL1A
- TNFSF15
- tumor necrosis factor (ligand) superfamily, member 15
- tumor necrosis factor ligand superfamily member 15
- vascular endothelial growth inhibitor-192A
- VEGI
- VEGI192A
- VEGITNF ligand-related molecule 1
Background
Tumor necrosis factor ligand superfamily member 15, also known TNFSF15, belongs to the TNF superfamily. TNFSF15 is predominantly expressed in endothelial cells and its expression is inducible by TNFalpha and IL1alpha. TNFSF15 is an angiogenesis inhibitor of the TNF family and functions in part by directly inhibiting endothelial cell proliferation. TNFSF15 may act as an autocrine factor to induce apoptosis in endothelial cells via activation of multiple signaling pathways, including stress protein kinases and certain caspases. Recombinant human TNFSF15 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.
product targets :　Haspin Kinase inhibitors