Recombinant Human TFF1/pS2 Protein Summary
A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 25-84 of Human TFF1/pS2
Source: E.coli
Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MEAQTETCTV APRERQNCGF PGVTPSQCAN KGCCFDDTVR GVPWCFYPNT IDVPPEEECE F
E. coli
Recombinant Protein
TFF1
>90%, by SDS-PAGE
Applications/Dilutions
9 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Packaging, Storage & Formulations
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 20% glycerol, 100mM NaCl, 0.1mM PMSF
No Preservative
0.5 mg/ml
>90%, by SDS-PAGE
Alternate Names for Recombinant Human TFF1/pS2 Protein
- BCEI
- BCEIbreast cancer, estrogen-inducible sequence expressed in
- Breast cancer estrogen-inducible protein
- breast cancer estrogen-inducible sequence
- D21S21
- gastrointestinal trefoil protein pS2
- hP1.A
- HPS2
- PNR-2
- Polypeptide P1.A
- Protein pS2
- PS2
- TFF1
- trefoil factor 1
- trefoil factor, BCE1, human pS2 induced by estrogen from human breast cancercell line M10HP1.A
Background
TFF1 (Trefoil factor 1) is member of trefoil family, characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. Trefoil peptides are protease resistant molecules secreted throughout the gut that play a role in mucosal healing. TFF1 has also been detected in a number of carcinomas including cancers of the breast, pancreas and stomach. Recombinant human TFF1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.
product targets :　Farnesyl Transferase inhibitors