Recombinant Human SIT1 Protein Summary
A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-196 of Human SIT1
Source: E.coli
Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MHLSQWTRGR SRSHPGQGRS GESVEEVPLY GNLHYLQTGR LSQDPEPDQQ DPTLGGPARA AEEVMCYTSL QLRPPQGRIP GPGTPVKYSE VVLDSEPKSQ ASGPEPELYA SVCAQTRRAR ASFPDQAYAN SQPAAS
E. coli
Recombinant Protein
SIT1
>90%, by SDS-PAGE
Applications/Dilutions
16.9 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Packaging, Storage & Formulations
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
20mM Tris-HCl buffer (pH8.0) containing 20% glycerol
No Preservative
0.25 mg/ml
>90%, by SDS-PAGE
Alternate Names for Recombinant Human SIT1 Protein
- gp30/40
- MGC125908
- MGC125909
- RP11-331F9.5
- SHP2 interacting transmembrane adaptor
- SHP2-interacting transmembrane adapter protein
- SHP2-interacting transmembrane adaptor protein
- signaling threshold regulating transmembrane adaptor 1
- signaling threshold-regulating transmembrane adapter 1
- SIT1
- SITMGC125910
- suppression inducing transmembrane adaptor 1
- Suppression-inducing transmembrane adapter 1
Background
SIT1, also known as signaling threshold-regulating transmembrane adapter 1, negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells. This protein involved in positive selection of T-cells. Recombinant human SIT1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.
product targets :　GHSR inhibitors