journal.pone.0150860

Recombinant Human S100A16 Protein Summary

    Description
    A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-103 of Human S100A16

    Source: E.coli

    Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MSDCYTELEK AVIVLVENFY KYVSKYSLVK NKISKSSFRE MLQKELNHML SDTGNRKAAD KLIQNLDANH DGRISFDEYW TLIGGITGPI AKLIHEQEQQ SSS

    Source
    E. coli
    Protein/Peptide Type
    Recombinant Protein
    Gene
    S100A16
    Purity
    >95% pure by SDS-PAGE

Applications/Dilutions

    Theoretical MW
    13.9 kDa.
    Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

    Storage
    Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
    Buffer
    20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 40% glycerol, 0.2M NaCl
    Preservative
    No Preservative
    Concentration
    1 mg/ml
    Purity
    >95% pure by SDS-PAGE

Alternate Names for Recombinant Human S100A16 Protein

      AAG13
      Aging-associated gene 13 protein
      aging-associated protein 13
      DT1P1A7
      MGC17528
      protein S100-A16
      Protein S100-F
      S100 calcium binding protein A16
      S100A16
      S100F
      S100FS100 calcium-binding protein A16

Background

S100 calcium binding protein A16, also known S100A16, is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. Intracellularly, S100A16 is both nuclear and cytoplasmic and apparently exists as a homodimer, trimer and tetramer. It contains two EF-hand motifs with only one high-affinity Ca-binding site and apparently undergoes phosphorylation at Ser103. Recombinant human S100A16 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

product targets : HIV Protease inhibitors

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