oncotarget.8026

Recombinant Human RPS3 Protein Summary

    Description
    A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-243 of Human RPS3

    Source: E.coli

    Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MAVQISKKRK FVADGIFKAE LNEFLTRELA EDGYSGVEVR VTPTRTEIII LATRTQNVLG EKGRRIRELT AVVQKRFGFP EGSVELYAEK VATRGLCAIA QAESLRYKLL GGLAVRRACY GVLRFIMESG AKGCEVVVSG KLRGQRAKSM KFVDGLMIHS GDPVNYYVDT AVRHVLLRQG VLGIKVKIML PWDPTGKIGP KKPLPDHVSI VEPKDEILPT TPISEQKGGK PEPPAMPQPV PTA

    Source
    E. coli
    Protein/Peptide Type
    Recombinant Protein
    Gene
    RPS3
    Purity
    >90%, by SDS-PAGE

Applications/Dilutions

    Theoretical MW
    28.8 kDa.
    Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

    Storage
    Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
    Buffer
    20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol, 0.1M NaCl
    Preservative
    No Preservative
    Concentration
    1 mg/ml
    Purity
    >90%, by SDS-PAGE

Alternate Names for Recombinant Human RPS3 Protein

      40S ribosomal protein S3
      FLJ26283
      FLJ27450
      IMR-90 ribosomal protein S3
      MGC87870
      ribosomal protein S3

Background

40S ribosomal protein S3, also known as RPS3, belongs to the S3P family of ribosomal proteins. RPS3 mediates the formation of the mRNA binding site 3 of the codon in the decoding site. In addition, RPS3 is involved in DNA damage recognition as shown by its affinity for abasic sites and 7, 8-dihydro-8-oxoguanine residues and its interaction with human base excision repair proteins OGG1 and Ref-1. Higher levels of expression of this gene in colon adenocarcinomas and adenomatous polyps compared to adjacent normal colonic mucosa have been observed. Recombinant human RPS3 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

product targets : mGluR inhibitors

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