fnana.2015.00160

Recombinant Human RBP4/Retinol-Binding Protein 4 Protein Summary

    Description
    Recombinant bioactive protein for Human RBP4/Retinol-Binding Protein 4

    Source:E. coli
    Amino Acid Sequence:(P02753)

    Details of Functionality
    Immune reactive in ELISA using monoclonal anti CD4 in gpl2O capture ELISA assays.
    Source
    E. coli
    Protein/Peptide Type
    Biologically Active Protein
    Gene
    RBP4
    Purity
    >95%, by SDS-PAGE

Applications/Dilutions

    Theoretical MW
    21 kDa.
    Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

    Storage
    Store at -20 to -80C. Avoid freeze-thaw cycles.
    Buffer
    Sterile filtered solution in PBS, pH 7.4
    Concentration
    1 mg/ml
    Purity
    >95%, by SDS-PAGE

Alternate Names for Recombinant Human RBP4/Retinol-Binding Protein 4 Protein

      interstitial
      Plasma retinol-binding protein
      RBP4
      retinol binding protein 4, plasma
      RetinolBinding Protein 4
      retinol-binding protein 4, plasma

Background

Retinol binding protein 4(RBP4) belongs to the lipocalin family and is the specific carrier for retinol (vitamin A alcohol) in the blood. This protein was found to be expressed and secreted by adipose tissue, and was strongly associated with insulin resistance. It delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin which prevents its loss by filtration through the kidney glomeruli.RBP4 delivers retinol from the liver to the peripheral tissues. In plasma, the rbp-retinol complex interacts with transthyretin, this prevents its loss by filtration through the kidney glomeruli. RBP-4 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 184 amino acids and having a molecular mass of 21 kDa. The Retinol Binding Protein-4 is purified by proprietary chromatographic techniques.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 2 years from date of receipt.

Crenolanib

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