Recombinant Human PTP4A1 Protein Summary
A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-170 of Human PTP4A1
Source: E.coli
Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MARMNRPAPV EVTYKNMRFL ITHNPTNATL NKFIEELKKY GVTTIVRVCE ATYDTTLVEK EGIHVLDWPF DDGAPPSNQI VDDWLSLVKI KFREEPGCCI AVHCVAGLGR APVLVALALI EGGMKYEDAV QFIRQKRRGA FNSKQLLYLE KYRPKMRLRF KDSNGHRNNC
E. coli
Recombinant Protein
PTP4A1
>90%, by SDS-PAGE
Applications/Dilutions
21.6 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Packaging, Storage & Formulations
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 0.1M NaCl, 1mM DTT
No Preservative
1 mg/ml
>90%, by SDS-PAGE
Alternate Names for Recombinant Human PTP4A1 Protein
- EC 3.1.3.48
- HH72
- PRL1
- PRL-1
- PRL-1DKFZp779M0721
- Protein tyrosine phosphatase IVA1
- protein tyrosine phosphatase type IVA 1
- protein tyrosine phosphatase type IVA protein 1
- protein tyrosine phosphatase type IVA, member 1
- Protein-tyrosine phosphatase 4a1
- Protein-tyrosine phosphatase of regenerating liver 1
- PTP(CAAX1)
- PTP(CAAXI)
- PTPCAAX1PRL1PTP(CAAX1)
Background
PTP4A1, also known as protein tyrosine phosphatase type IVA 1, is cell signaling molecule that plays regulatory roles in a variety of cellular processes. This protein is a unique nuclear PTP that is induced in regenerating liver and mitogen stimulated cells. It is primarily expressed in spleen, bone marrow, thymus, lymph nodes, T lymphocytes and tonsil and is overexpressed in tumor cell lines. Recombinant human PTP4A1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.
product targets :　Adenylate Cyclase inhibitors