pdia.2015.48037

Recombinant Human PITPNB Protein Summary

    Description
    A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-271 of Human PITPNB

    Source: E.coli

    Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MVLIKEFRVV LPCSVQEYQV GQLYSVAEAS KNETGGGEGI EVLKNEPYEK DGEKGQYTHK IYHLKSKVPA FVRMIAPEGS LVFHEKAWNA YPYCRTIVTN EYMKDDFFIK IETWHKPDLG TLENVHGLDP NTWKTVEIVH IDIADRSQVE PADYKADEDP ALFQSVKTKR GPLGPNWKKE LANSPDCPQM CAYKLVTIKF KWWGLQSKVE NFIQKQEKRI FTNFHRQLFC WIDKWIDLTM EDIRRMEDET QKELETMRKR GSVRGTSAAD V

    Source
    E. coli
    Protein/Peptide Type
    Recombinant Protein
    Gene
    PITPNB
    Purity
    >95% pure by SDS-PAGE

Applications/Dilutions

    Theoretical MW
    33.7 kDa.
    Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

    Storage
    Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
    Buffer
    20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol
    Preservative
    No Preservative
    Concentration
    1 mg/ml
    Purity
    >95% pure by SDS-PAGE

Alternate Names for Recombinant Human PITPNB Protein

      phosphatidylinositol transfer protein beta isoform
      phosphatidylinositol transfer protein, beta
      phosphotidylinositol transfer protein, beta
      PI-TP-beta
      PtdIns transfer protein beta
      PtdInsTP beta
      PtdInsTP
      VIB1B

Background

Phosphatidylinositol transfer protein beta isoform, also known PITPNB, is found in the cytoplasm, where it catalyzes the transfer of phosphatidylinositol (PI) and phosphatidylcholine (PC) between membranes. PITPNB mobilizes PI from the endoplasmic recticulum and regulates the release of PI from stored vesicles in the Golgi network. PITPNB is widely expressed in various tissues. Recombinant human PITPNB protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

product targets : Tryptophan Hydroxylase inhibitors

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